Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda

被引：27

作者：

Hahn, Judith A. ^{[1
]}

Bwana, Mwebesa B. ^{[2
]}

Javors, Martin A. ^{[3
]}

Martin, Jeffrey N. ^{[1
]}

Emenyonu, Nneka I. ^{[4
]}

Bangsberg, David R. ^{[2
,4
]}

机构：

[1] Univ Calif San Francisco, San Francisco, CA 94143 USA

[2] Mbarara Univ Sci & Technol, Mbarara, Uganda

[3] Univ Texas Hlth Sci Ctr, San Antonio, TX USA

[4] Massachusetts Gen Hosp, Boston, MA 02114 USA

来源：

AIDS AND BEHAVIOR | 2010年 / 14卷 / 06期

关键词：

Carbohydrate-deficient transferrin; Biological markers; Alcohol drinking; HIV; Antiretroviral therapy; Uganda; CARBOHYDRATE-DEFICIENT TRANSFERRIN; METAANALYSIS; HPLC; CDT;

D O I：

10.1007/s10461-010-9768-y

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferin (%CDT), a biomarker of heavy alcohol consumption in persons initiating antiretroviral therapy in Uganda Almost seven percent (6 7%) of persons reporting abstaining and 10% reporting consuming 1-40 drinks in the prior month tested positive for %CDT, and actual under-report may be higher due to low sensitivity of %CDT These results suggest likely under-report in those reporting abstaining and current drinking Improved identification of heavy alcohol consumption is needed for research and clinical purposes

引用

页码：1265 / 1268

页数：4

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