Quantifying tracer levels of 2H2O enrichment from microliter amounts of plasma and urine by 2H NMR

被引：0

作者：

Jones, JG ^{[1
]}

Merritt, M ^{[1
]}

Malloy, C ^{[1
]}

机构：

[1] Univ Texas, SW Med Ctr, Dept Radiol, Mary Nell & Ralph B Rogers Magnet Resonance Ctr, Dallas, TX 75235 USA

来源：

MAGNETIC RESONANCE IN MEDICINE | 2001年 / 45卷 / 01期

关键词：

body water; deuterium; gluconeogenesis; tracer; biosynthetic pathways;

D O I：

10.1002/1522-2594(200101)45:1<156::AID-MRM1020>3.0.CO;2-Z

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A simple and sensitive H-2 NMR measurement of (H2O)-H-2 enrichment from a 10 mul volume of body fluid is presented, The method allows H-2-enrichment levels of 0.1% or above to be rapidly determined from 10 pi of plasma or urine, The measurement is insensitive to the presence of plasma protein, allowing direct analysis of (H2O)-H-2 enrichment from native plasma samples, Magn Reson Med 45: 156-158, 2001, (C) 2001 Wiley-Liss, Inc.

引用

页码：156 / 158

页数：3

共 14 条

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