Amphiphilic peptides as novel nanomaterials: design, self-assembly and application

被引：84
作者：
Qiu, Feng [1 ,2 ]
Chen, Yongzhu [2 ,3 ]
Tang, Chengkang [2 ,4 ]
Zhao, Xiaojun [2 ]
机构：
[1] Sichuan Univ, West China Hosp, Lab Anaesthesia & Crit Care Med, Translat Neurosci Ctr, B2 Bldg,88 Keyuan South Rd, Chengdu 610041, Sichuan, Peoples R China
[2] Sichuan Univ, West China Hosp, Inst Nanobiomed Technol & Membrane Biol, 1,Keyuan 4th Rd, Chengdu 610041, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp, Period Press, Chengdu 610041, Sichuan, Peoples R China
[4] Sichuan Univ, West China Hosp, Core Facil, Chengdu 610041, Sichuan, Peoples R China
来源：
INTERNATIONAL JOURNAL OF NANOMEDICINE | 2018年 / 13卷
基金：
中国国家自然科学基金;
关键词：
amphiphilic peptides; self-assembly; nanomaterials; SURFACTANT-LIKE PEPTIDES; TISSUE-ENGINEERING SCAFFOLDS; IN-VITRO; EFFICIENT GENE; REGENERATIVE MEDICINE; BOLAAMPHIPHILIC PEPTIDES; HYDROPHOBIC COMPOUNDS; PROGENITOR CELLS; FORM NANOTUBES; DRUG CARRIERS;
D O I：
10.2147/IJN.S166403
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Designer self-assembling peptides are a category of emerging nanobiomaterials which have been widely investigated in the past decades. In this field, amphiphilic peptides have received special attention for their simplicity in design and versatility in application. This review focuses on recent progress in designer amphiphilic peptides, trying to give a comprehensive overview about this special type of self-assembling peptides. By exploring published studies on several typical types of amphiphilic peptides in recent years, herein we discuss in detail the basic design, self-assembling behaviors and the mechanism of amphiphilic peptides, as well as how their nanostructures are affected by the peptide characteristics or environmental parameters. The applications of these peptides as potential nanomaterials for nanomedicine and nanotechnology are also summarized.
引用
收藏
页码：5003 / 5022
页数：20
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