Aviram-Ratner rectifying mechanism for DNA base-pair sequencing through graphene nanogaps

被引：12

作者：

Agapito, Luis A. ^{[1
,2
]}

Gayles, Jacob ^{[1
,2
,3
]}

Wolowiec, Christian ^{[1
,2
,4
]}

Kioussis, Nicholas ^{[1
,2
]}

机构：

[1] Calif State Univ Northridge, Dept Phys, Northridge, CA 91330 USA

[2] Calif State Univ Northridge, WM Keck Computat Mat Theory Ctr, Northridge, CA 91330 USA

[3] Texas A&M Univ, Dept Phys, College Stn, TX 77843 USA

[4] Univ Calif San Diego, Dept Phys, La Jolla, CA 92093 USA

来源：

NANOTECHNOLOGY | 2012年 / 23卷 / 13期

关键词：

TRANSVERSE ELECTRONIC TRANSPORT; SCANNING TUNNELING MICROSCOPE; MOLECULES; NANOPORE; NUCLEOTIDES; PSEUDOPOTENTIALS; CONDUCTANCE; ENVIRONMENT; COLLOQUIUM; MEMBRANES;

D O I：

10.1088/0957-4484/23/13/135202

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

We demonstrate that biological molecules such as Watson-Crick DNA base pairs can behave as biological Aviram-Ratner electrical rectifiers because of the spatial separation and weak hydrogen bonding between the nucleobases. We have performed a parallel computational implementation of the ab initio non-equilibrium Green's function (NEGF) theory to determine the electrical response of graphene-base-pair-graphene junctions. The results show an asymmetric (rectifying) current-voltage response for the cytosine-guanine base pair adsorbed on a graphene nanogap. In sharp contrast we find a symmetric response for the thymine-adenine case. We propose applying the asymmetry of the current-voltage response as a sensing criterion to the technological challenge of rapid DNA sequencing via graphene nanogaps.

引用

页数：11

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