Determinants of 1-year changes in disease-specific health status in patients with advanced chronic obstructive pulmonary disease: A 1-year observational study

被引：6
作者：
Wilke, Sarah [1 ]
Spruit, Martijn A. [1 ]
Wouters, Emiel F. M. [2 ,3 ]
Schols, Jos M. G. A. [4 ,5 ]
Franssen, Frits M. E. [1 ]
Janssen, Daisy J. A. [1 ]
机构：
[1] CIRO Ctr Expertise Chron Organ Failure, Program Dev Ctr, NL-6085 NM Horn, Netherlands
[2] CIRO Ctr Expertise Chron Organ Failure, Program Dev Ctr, Resp Med, NL-6085 NM Horn, Netherlands
[3] MUMC, Resp Med, Dept Resp Med, Maastricht, Netherlands
[4] Maastricht Univ, Old Age Med, Dept Gen Practice, Fac Hlth Med & Life Sci CAPHRI, NL-6200 MD Maastricht, Netherlands
[5] Maastricht Univ, Dept Hlth Serv Res, Fac Hlth Med & Life Sci CAPHRI, NL-6200 MD Maastricht, Netherlands
来源：
INTERNATIONAL JOURNAL OF NURSING PRACTICE | 2015年 / 21卷 / 03期
关键词：
care dependency; dyspnoea; health-related quality of life; St George's Respiratory Questionnaire; Timed Up and Go test; QUALITY-OF-LIFE; CHRONIC HEART-FAILURE; COPD PATIENTS; DEPRESSIVE SYMPTOMS; REPORTED OUTCOMES; PHYSICAL-ACTIVITY; CARE DEPENDENCY; DYSPNEA; ASTHMA; EXACERBATIONS;
D O I：
10.1111/ijn.12265
中图分类号：
R47 [护理学];
学科分类号：
1011 ;
摘要：
We aimed to identify baseline and longitudinal determinants of change in disease-specific health status in patients with advanced chronic obstructive pulmonary disease (COPD). Demographic and clinical characteristics as well as disease-specific health status (St George's Respiratory Questionnaire, SGRQ) were assessed in 105 outpatients with advanced COPD at baseline and at 4, 8 and 12 months. Eighty-five patients (81.0%) had complete SGRQ data at baseline and 12 months and were included in analyses. Stepwise multiple regression analysis revealed that lower SGRQ total score, higher depression scores and longer time needed to complete the Timed Up and Go (TUG) test at baseline, as well as increase in time needed to complete the TUG test and increase in dyspnoea during the 1-year follow-up period, were predictors of deterioration in disease-specific health status. The current study reinforces the stimulation of physical mobility and the targeting of dyspnoea as components for treatment programs to optimize disease-specific health status in patients with advanced COPD.
引用
收藏
页码：239 / 248
页数：10
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