Antimicrobial potential of Glycyrrhiza glabra roots

被引：155

作者：

Gupta, Vivek K. ^{[1
]}

Fatima, Atiya ^{[1
]}

Faridi, Uzma ^{[1
]}

Negi, Arvind S. ^{[2
]}

Shanker, Karuna ^{[2
]}

Kumar, J. K. ^{[2
]}

Rahuja, Neha ^{[1
]}

Luqman, Suaib ^{[1
]}

Sisodia, Brijesh S. ^{[1
]}

Saikia, Dharmendra ^{[1
]}

Darokar, M. P. ^{[1
]}

Khanuja, Suman P. S. ^{[1
]}

机构：

[1] Cent Inst Med & Aromat Plants, Genet Resources & Biotechnol Div, Lucknow 226015, Uttar Pradesh, India

[2] Cent Inst Med & Aromat Plants, Div Analyt Chem, Lucknow 226015, Uttar Pradesh, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2008年 / 116卷 / 02期

关键词：

licorice; Glycyrrhiza glabra; glabridin; antibacterial; antitubercular;

D O I：

10.1016/j.jep.2007.11.037

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 mu g/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H37Ra and H(37)Rv strains at 29.16 mu g/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：377 / 380

页数：4

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