BIOCHEMICAL EFFECTS OF GINGER AND/OR GREEN TEA EXTRACTS IN HIGH FAT DIET - INDUCED OBESE RATS

The current study was designed to clarify the sequel of administration of green tea and/or extract of ginger on body weight, lipid profile, some hormones and some fertility variables in high fat diet (HFD) - induced obese rats. The results revealed that treatment of HFD obese rats with ginger extract decreased the elevated body weight (from 530 +/- 5.29 to 295 +/- 9.11), lee index (from 0.33 +/- 0.008 to 0.27 +/- 0.004), serum total cholesterol (from 25 +/- 2.57 to 187 +/- 2.79), triacylglycerol (TAG) (from 201 +/- 2.15 to154 +/- 1.82), low density lipoprotein cholesterol (LDL-C) (from 187.8 +/- 3.36 to119.6 +/- 2.31), very low density lipoprotein cholesterol (VLDL-C) (from 40.21 +/- 0.12 to 30.8 +/- 0.13), leptin (from 7.74 +/- 0.05 to 5.66 +/- 0.09), luetinzing hormone (LH) (from 0.30 +/- 0.006 to 0.19 +/- 0.005) and follicular stimulating hormone (FSH) (from 0.74 +/- 0.128 to 0.52 +/- 0.012) levels, but significantly elevated the decreased high density lipoprotein cholesterol (HDL-C) (from 21.40 +/- 0.50 to 36.40 +/- 0.81), serum testosterone (from 0.84 +/- 0.02 to 1.32 +/- 0.14), sperm count (from 44.20 +/- 2.08 to 65.20 +/- 0.54), motility (from 64 +/- 1.18 to 75.60 +/- 0.81) and normality (from 53.80 +/- 1.42 to 67 +/- 1.51). Similar results were observed with green tea treatment with minor variations. So, the inclusive outcomes may suggest that extracts of ginger and/or green tea have a significant hypolipidemic effect with body weight reduction in rats fed high fat diet. In addition, the extracts may be qualified for ameliorative the ruined fertility parameters.