Supportive Care During Pediatric Hematopoietic Stem Cell Transplantation: Prevention of Infections. A Report From Workshops on Supportive Care of the Paediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT)

被引：30

作者：

Ifversen, Marianne ^{[1
]}

Meisel, Roland ^{[2
]}

Sedlacek, Petr ^{[3
]}

Kalwak, Krzysztof ^{[4
]}

Sisinni, Luisa ^{[5
]}

Hutt, Daphna ^{[6
]}

Lehrnbecher, Thomas ^{[7
]}

Balduzzi, Adriana ^{[8
]}

Diesch, Tamara ^{[9
]}

Jarisch, Andrea ^{[10
]}

Gungor, Tayfun ^{[11
]}

Stein, Jerry ^{[12
]}

Yaniv, Isaac ^{[12
]}

Bonig, Halvard ^{[13
]}

Kuhlen, Michaela ^{[14
]}

Ansari, Marc ^{[15
,16
]}

Nava, Tiago ^{[15
,16
]}

Dalle, Jean-Hugues ^{[17
,18
]}

Diaz-de-Heredia, Cristina ^{[19
]}

Trigoso, Eugenia ^{[20
]}

Falkenberg, Ulrike ^{[21
]}

Hartmann, Mihaela ^{[21
]}

Deiana, Marco ^{[22
]}

Canesi, Marta ^{[8
]}

Broggi, Chiara ^{[8
]}

Bertaina, Alice ^{[23
,24
]}

Gibson, Brenda ^{[25
]}

Krivan, Gergely ^{[26
]}

Vettenranta, Kim ^{[27
,28
]}

Matic, Toni ^{[29
]}

Buechner, Jochen ^{[30
]}

Lawitschka, Anita ^{[21
]}

Peters, Christina ^{[21
]}

Yesilipek, Akif ^{[31
,32
]}

Yalcin, Koray ^{[33
]}

Lucchini, Giovanna ^{[34
]}

Bakhtiar, Shahrzad ^{[10
]}

Turkiewicz, Dominik ^{[35
]}

Niinimaki, Riitta ^{[36
]}

Wachowiak, Jacek ^{[37
]}

Cesaro, Simone ^{[38
]}

Dalissier, Arnaud ^{[39
]}

Corbacioglu, Selim ^{[40
]}

Willasch, Andre Manfred ^{[10
]}

Bader, Peter ^{[10
]}

机构：

[1] Copenhagen Univ Hosp, Dept Paediat & Adolescent Med, Rigshospitalet, Copenhagen, Denmark

[2] Heinrich Heine Univ, Dept Pediat Oncol Hematol & Clin Immunol, Div Pediat Stem Cell Therapy, Med Fac, Dusseldorf, Germany

[3] Charles Univ Prague, Hosp Motol, Dept Pediat Hematol & Oncol, Prague, Czech Republic

[4] Wroclaw Med Univ, Dept Pediat Hematol Oncol & Bone Marrow Transplan, Wroclaw, Poland

[5] Hosp Santa Creu & Sant Pau, Pediat Hematol Oncol & Hematopoiet Stem Cell Tran, Barcelona, Spain

[6] Edmond & Lily Safra Childrens Hosp, Div Pediat Hematol Oncol & Bone Marrow Transplant, Tel Aviv, Israel

[7] Goethe Univ, Univ Hosp, Hosp Children & Adolescents, Div Pediat Hematol & Oncol, Frankfurt, Germany

[8] Univ Milano Bicocca, Clin Pediat, Fdn Monza & Brianza Bambino & Sua Mamma, Osped San Gerardo, Monza, Italy

[9] Univ Childrens Hosp Basel, Div Pediat Hematol Oncol, Basel, Switzerland

[10] Goethe Univ, Univ Hosp, Hosp Children & Adolescents, Div Stem Cell Transplantat Immunol & Intens Care, Frankfurt, Germany

[11] Univ Childrens Hosp Zurich, Dept Hematol Immunol Oncol & Stem Cell Transplant, Zurich, Switzerland

[12] Schneider Childrens Med Ctr Israel, Div Pediat Hematoloy Oncol, Petah Tiqwa, Israel

[13] Goethe Univ, German Red Cross Blood Serv Baden Wurttemberg Hes, Inst Transfus Med & Immunohematol, Frankfurt, Germany

[14] Univ Augsburg, Med Fac, Paediat & Adolescent Med, Augsburg, Germany

[15] Univ Hosp Geneva, Div Pediat Hematol Oncol, Geneva, Switzerland

[16] Univ Geneva, Dept Paediat Gynaecol & Obstet, Cansearch Res Platform Paediat Oncol & Haematol, Fac Med, Geneva, Switzerland

[17] Robert Debre Hosp, AP HP, Hematol & Immunol Dept, Paris, France

[18] Univ Paris, Paris, France

[19] Hosp Univ Vall dHebron, Dept Pediat Oncol & Hematol, Barcelona, Spain

[20] Hosp Univ & Polytech, Hosp LA FE, Paediat Transplant Unit, Valencia, Spain

[21] Med Univ Vienna, St Anna Childrens Hosp, Dept Pediat, Stem Cell Transplantat Unit, Vienna, Austria

[22] Ist Ricovero & Cura Carattere Sci G Gaslini, Paediat Haematol Oncol Dept, Genoa, Italy

[23] Bambino Gesu Pediat Hosp, Dept Pediat Hematol Oncol & Cell & Gene Therapy, Ist Ricovero & Cura Carattere Sci, Rome, Italy

[24] Stanford Univ, Sch Med, Dept Pediat, Div Stem Cell Transplantat & Regenerat Med, Stanford, CA 94305 USA

[25] Royal Hosp Children, Dept Paediat Haematol Oncol, Glasgow, Lanark, Scotland

[26] Cent Hosp Southern Pest, Natl Inst Hematol & Infect Dis, Budapest, Hungary

[27] Univ Helsinki, Childrens Hosp, Helsinki, Finland

[28] Univ Helsinki, Pediat Res Ctr, Helsinki, Finland

[29] Univ Hosp Ctr Zagreb, Dept Pediat, Zagreb, Croatia

[30] Oslo Univ Hosp, Dept Pediat Hematol & Oncol, Oslo, Norway

[31] Antalya & Goztepe Medicalpark Hosp, Dept Pediat Hematol, Antalya, Turkey

[32] Antalya & Goztepe Medicalpark Hosp, Pediat Stem Cell Transplantat Unit, Antalya, Turkey

[33] Medicalpark Goztepe Hosp, Dept Pediat, Bone Marrow Transplantat Unit, Istanbul, Turkey

[34] Great Ormond St Hosp Sick Children, Dept Bone Marrow Transplantat, Natl Hlth Serv Fdn Trust, London, England

[35] Lund Univ, Div Mol Hematol, Lund, Sweden

[36] Oulu Univ Hosp, Dept Pediat, Oulu, Finland

[37] Poznan Univ Med Sci, Dept Pediat Oncol Hematol & Hematopoiet Stem Cell, Poznan, Poland

[38] Azienda Osped Univ Integrata, Dept Mother & Child, Pediat Hematol Oncol, Verona, Italy

[39] Hop St Antoine, European Soc Blood & Marrow Transplantat Paris Of, Paris, France

[40] Univ Hosp Regensburg, Dept Pediat Hematol Oncol & Stem Cell Transplanta, Regensburg, Germany

来源：

FRONTIERS IN PEDIATRICS | 2021年 / 9卷

关键词：

infection precaution; allogeneic hematological stem cell transplantation; children; antibiotic prophylactic therapy; vaccination; PARTICULATE AIR FILTRATION; NEUTROPENIC DIET; RECIPIENTS; GUIDELINES; PROPHYLAXIS; COMPLICATIONS; CHILDREN; LEUKEMIA; CHEMOTHERAPY; CANCER;

D O I：

10.3389/fped.2021.705179

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Specific protocols define eligibility, conditioning, donor selection, graft composition and prophylaxis of graft vs. host disease for children and young adults undergoing hematopoietic stem cell transplant (HSCT). However, international protocols rarely, if ever, detail supportive care, including pharmaceutical infection prophylaxis, physical protection with face masks and cohort isolation or food restrictions. Supportive care suffers from a lack of scientific evidence and implementation of practices in the transplant centers brings extensive restrictions to the child's and family's daily life after HSCT. Therefore, the Board of the Pediatric Diseases Working Party (PDWP) of the European Society for Blood and Marrow Transplantation (EBMT) held a series of dedicated workshops since 2017 with the aim of initiating the production of a set of minimal recommendations. The present paper describes the consensus reached within the field of infection prophylaxis.

引用

页数：13

共 70 条

[1] Administration FUSFAD, FOOD SAF PEOPL CANC
[2] Epstein-Barr virus-related post-transplant lymphoproliferative disease (EBV-PTLD) in the setting of allogeneic stem cell transplantation: a comprehensive review from pathogenesis to forthcoming treatment modalities
Al Hamed, Rama
Bazarbachi, Abdul Hamid
Mohty, Mohamad
[J]. BONE MARROW TRANSPLANTATION, 2020, 55 (01) : 25 - 39
[3] Effect of Levofloxacin Prophylaxis on Bacteremia in Children With Acute Leukemia or Undergoing Hematopoietic Stem Cell Transplantation A Randomized Clinical Trial
Alexander, Sarah
Fisher, Brian T.
Gaur, Aditya H.
Dvorak, Christopher C.
Luna, Doojduen Villa
Dang, Ha
Chen, Lu
Green, Michael
Nieder, Michael L.
Fisher, Beth
Bailey, L. Charles
Wiernikowski, John
Sung, Lillian
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2018, 320 (10): : 995 - 1004
[4] Real-World Issues and Potential Solutions in Hematopoietic Cell Transplantation during the COVID-19 Pandemic: Perspectives from the Worldwide Network for Blood and Marrow Transplantation and Center for International Blood and Marrow Transplant Research Health Services and International Studies Committee
Algwaiz, Ghada
Aljurf, Mahmoud
Koh, Mickey
Horowitz, Mary M.
Ljungman, Per
Weisdorf, Daniel
Saber, Wael
Kodera, Yoshihisa
Szer, Jeff
Jawdat, Dunia
Wood, William A.
Brazauskas, Ruta
Lehmann, Leslie
Pasquini, Marcelo C.
Seber, Adriana
Lu, Pei Hua
Atsuta, Yoshiko
Riches, Marcie
Perales, Miguel-Angel
Worel, Nina
Okamoto, Shinichiro
Srivastava, Alok
Chemaly, Roy F.
Cordonnier, Catherine
Dandoy, Christopher E.
Wingard, John R.
Kharfan-Dabaja, Mohamed A.
Hamadani, Mehdi
Majhail, Navneet S.
Waghmare, Alpana A.
Chao, Nelson
Kroger, Nicolaus
Shaw, Bronwen
Mohty, Mohamad
Niederwieser, Dietger
Greinix, Hildegard
Hashmi, Shahrukh K.
[J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2020, 26 (12) : 2181 - 2189
[5] [Anonymous], 2013, MMWR RECOMMEND REP, V62, P1
[6] Lessons after the early management of the COVID-19 outbreak in a pediatric transplant and hemato-oncology center embedded within a COVID-19 dedicated hospital in Lombardia, Italy. Estote parati
Balduzzi, Adriana
Brivio, Erica
Rovelli, Attilio
Rizzari, Carmelo
Gasperini, Serena
Melzi, Maria Luisa
Conter, Valentino
Biondi, Andrea
[J]. BONE MARROW TRANSPLANTATION, 2020, 55 (10) : 1900 - 1905
[7] Handwashing compliance by health care workers -: The impact of introducing an accessible, alcohol-based hand antiseptic
Bischoff, WE
Reynolds, TM
Sessler, CN
Edmond, MB
Wenzel, RP
[J]. ARCHIVES OF INTERNAL MEDICINE, 2000, 160 (07) : 1017 - 1021
[8] Bolyard EA, 1998, INFECT CONT HOSP EP, V19, P407
[9] Preventing transmission of infectious agents in the pediatric in-patients hematology-oncology setting: what is the role for non-pharmacological prophylaxis?
Caselli, Desiree
Cesaro, Simone
Livadiotti, Susanna
Ziino, Ottavio
Paolicchi, Olivia
Zanazzo, Guilio
Milano, Giuseppe M.
Licciardello, Maria
Barone, Angelica
Cellini, Monica
Raffaella, De Santis
Giacchino, Mareva
Rossi, Mario Renato
Arico, Maurizio
Castagnola, Elio
[J]. PEDIATRIC REPORTS, 2011, 3 (01) : 27 - 30
[10] Clinical utility of measuring Epstein-Barr virus-specific cell-mediated immunity after HSCT in addition to virological monitoring: results from a prospective study
Chiereghin, Angela
Piccirilli, Giulia
Belotti, Tamara
Prete, Arcangelo
Bertuzzi, Clara
Gibertoni, Dino
Gabrielli, Liliana
Turello, Gabriele
Borgatti, Eva Caterina
Barbato, Francesco
Sessa, Mariarosaria
Arpinati, Mario
Bonifazi, Francesca
Lazzarotto, Tiziana
[J]. MEDICAL MICROBIOLOGY AND IMMUNOLOGY, 2019, 208 (06) : 825 - 834

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