Evolution of Therapy for Relapsed/Refractory Multiple Myeloma

被引：4

作者：

Castillo, Jorge J. ^{[1
]}

机构：

[1] Dana Farber Canc Inst, 450 Brookline Ave,M221, Boston, MA 02215 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2019年 / 17卷 / 11期

关键词：

PLUS POMALIDOMIDE; DEXAMETHASONE; LENALIDOMIDE; DARATUMUMAB; BORTEZOMIB;

D O I：

10.6004/jnccn.2019.5035

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

With so many recent advances in relapsed/refractory multiple myeloma, keeping abreast with current treatment recommendations can be challenging. Novel immunomodulators, proteasome inhibitors, monoclonal antibodies, histone deacetylase inhibitors, and nuclear export inhibitors have all been added to the armamentarium, and the choice of which of these drugs or drug combinations to use depends on individual disease-related and patient-related factors, previous therapies, and treatment toxicities. At the NCCN 2019 Annual Congress: Hematologic Malignancies, Dr. Jorge J. Castillo provided an overview of the myriad treatments available for patients with relapsed/refractory multiple myeloma, as well as therapies on the horizon.

引用

页码：1433 / 1436

页数：4

共 50 条

[41] Updates on Therapeutic Strategies in the Treatment of Relapsed/Refractory Multiple Myeloma [J].

Parekh, Deevyashali S. ;

Tiger, Yun Kyoung Ryu ;

Jamouss, Kevin Tony ;

Hassani, Justin ;

Bou Zerdan, Maroun ;

Raza, Shahzad .

CANCERS, 2024, 16 (17)

[42] Perifosine plus lenalidomide and dexamethasone in relapsed and relapsed/refractory multiple myeloma: a Phase I Multiple Myeloma Research Consortium study [J].

Jakubowiak, Andrzej J. ;

Richardson, Paul G. ;

Zimmerman, Todd ;

Alsina, Melissa ;

Kaufman, Jonathan L. ;

Kandarpa, Malathi ;

Kraftson, Stephanie ;

Ross, Charles W. ;

Harvey, Colleen ;

Hideshima, Teru ;

Sportelli, Peter ;

Poradosu, Enrique ;

Gardner, Lesa ;

Giusti, Kathy ;

Anderson, Kenneth C. .

BRITISH JOURNAL OF HAEMATOLOGY, 2012, 158 (04) :472-480

[43] Safety of prolonged therapy with bortezomib in relapsed or refractory multiple myeloma [J].

Berenson, JR ;

Jagannath, S ;

Barlogie, B ;

Siegel, DT ;

Alexanian, R ;

Richardson, PG ;

Irwin, D ;

Alsina, M ;

Rajkumar, SV ;

Srkalovic, G ;

Singhal, S ;

Limentani, S ;

Niesvizky, R ;

Esseltine, DL ;

Trehu, E ;

Schenkein, DP ;

Anderson, K .

CANCER, 2005, 104 (10) :2141-2148

[44] Salvage therapy with bortezomib and dexamethasone in elderly patients with relapsed/refractory multiple myeloma [J].

Castelli, Roberto ;

Pantaleo, Giuseppe ;

Gallipoli, Paolo ;

Gidaro, Antonio ;

Arquati, Massimo ;

Wu, Maddalena A. ;

Deliliers, Giorgio Lambertenghi .

ANTI-CANCER DRUGS, 2015, 26 (10) :1078-1082

[45] Review of therapy for relapsed/refractory multiple myeloma: focus on lenalidomide [J].

Mariz, Jose Mario ;

Esteves, Graca Vasconcelos .

CURRENT OPINION IN ONCOLOGY, 2012, 24 :S3-S12

[46] Emerging Targets and Cellular Therapy for Relapsed Refractory Multiple Myeloma: A Systematic Review [J].

George, Laeth L. ;

Deshpande, Saarang R. ;

Cortese, Matthew J. ;

Kendall, Ellen K. ;

Chattaraj, Asmi ;

Shah, Zunairah ;

Zhao, Jianjun ;

Anwer, Faiz .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2021, 21 (11) :741-751

[47] Bortezomib plus dexamethasone vs thalidomide plus dexamethasone for relapsed or refractory multiple myeloma [J].

Iida, Shinsuke ;

Wakabayashi, Masashi ;

Tsukasaki, Kunihiro ;

Miyamoto, Kenichi ;

Maruyama, Dai ;

Yamamoto, Kazuhito ;

Takatsuka, Yoshifusa ;

Kusumoto, Shigeru ;

Kuroda, Junya ;

Ando, Kiyoshi ;

Kikukawa, Yoshitaka ;

Masaki, Yasufumi ;

Kobayashi, Miki ;

Hanamura, Ichiro ;

Asai, Hiroaki ;

Nagai, Hirokazu ;

Shimada, Kazuyuki ;

Tsukamoto, Norifumi ;

Inoue, Yoshiko ;

Tobinai, Kensei .

CANCER SCIENCE, 2018, 109 (05) :1552-1561

[48] Pomalidomide alone or in combination with dexamethasone in Japanese patients with refractory or relapsed and refractory multiple myeloma [J].

Matsue, Kosei ;

Iwasaki, Hiromi ;

Chou, Takaaki ;

Tobinai, Kensei ;

Sunami, Kazutaka ;

Ogawa, Yoshiaki ;

Kurihara, Mari ;

Midorikawa, Shuichi ;

Zaki, Mohamed ;

Doerr, Thomas ;

Iida, Shinsuke .

CANCER SCIENCE, 2015, 106 (11) :1561-1567

[49] Treatment of relapsed and refractory multiple myeloma [J].

Seema Singhal ;

Jayesh Mehta .

Current Treatment Options in Oncology, 2003, 4 (3) :229-237

[50] Melflufen for relapsed and refractory multiple myeloma [J].

Oriol, Albert ;

Larocca, Alessandra ;

Leleu, Xavier ;

Hajek, Roman ;

Hassoun, Hani ;

Rodriguez-Otero, Paula ;

Paner, Agne ;

Schjesvold, Fredrik H. ;

Gullbo, Joachim ;

Richardson, Paul G. .

EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2020, 29 (10) :1069-1078

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