A novel preparation of methyl ketones through one-carbon homologation of aldehydes

被引：10

作者：

Wang, L ^{[1
]}

Li, PH

Yan, JC

Wu, ZZ

机构：

[1] Huaibei Coal Teachers Coll, Dept Chem, Huaibei 235000, Anhui, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

[3] Univ Tennessee, Dept Chem, Knoxville, TN 37996 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 25期

基金：

中国国家自然科学基金;

关键词：

1,1-dibromo-1-alkene; near-critical water; zinc metal; homologation; methyl ketone; aldehyde;

D O I：

10.1016/S0040-4039(03)01084-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel two-step aldehyde homologation procedure for the preparation of methyl ketones has been developed, which involves the use of 1,1-dibromo-1-alkenes as precursors and zinc metal as mediator in near-critical water. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：4685 / 4688

页数：4

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