Zero-field remote detection of NMR with a microfabricated atomic magnetometer

被引：110

作者：

Ledbetter, M. P. ^{[2
]}

Savukov, I. M. ^{[2
]}

Budker, D. ^{[2
,3
]}

Shah, V. ^{[4
]}

Knappe, S. ^{[4
]}

Kitching, J. ^{[4
]}

Michalak, D. J. ^{[1
]}

Xu, S. ^{[1
]}

Pines, A. ^{[1
]}

机构：

[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Phys, Berkeley, CA 94720 USA

[3] Lawrence Berkeley Natl Lab, Div Nucl Sci, Berkeley, CA 94720 USA

[4] Natl Inst Stand & Technol, Div Time & Frequency, Boulder, CO 80305 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2008年 / 105卷 / 07期

关键词：

microfluidics; signal-to-noise ratio; mass-limited sample;

D O I：

10.1073/pnas.0711505105

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We demonstrate remote detection of nuclear magnetic resonance (NMR) with a microchip sensor consisting of a microfluidic channel and a microfabricated vapor cell (the heart of an atomic magnetometer). Detection occurs at zero magnetic field, which allows operation of the magnetometer in the spin-exchange relaxation-free (SERF) regime and increases the proximity of sensor and sample by eliminating the need for a solenoid to create a leading field. We achieve pulsed NMR linewidths of 26 Hz, limited, we believe, by the residence time and flow dispersion in the encoding region. In a fully optimized system, we estimate that for 1 s of integration, 7 x 10(13) protons in a volume of 1 mm(3), prepolarized in a 10-kG field, can be detected with a signal-to-noise ratio of approximate to 3. This level of sensitivity is competitive with that demonstrated by microcoils in 100-kG magnetic fields, without requiring superconducting magnets.

引用

页码：2286 / 2290

页数：5

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