Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection

被引：82

作者：

Barteneva, N ^{[1
]}

Theodor, I ^{[1
]}

Peterson, EM ^{[1
]}

delaMaza, LM ^{[1
]}

机构：

[1] UNIV CALIF IRVINE,DEPT PATHOL MED SCI 1,IRVINE,CA 92697

来源：

INFECTION AND IMMUNITY | 1996年 / 64卷 / 11期

关键词：

D O I：

10.1128/IAI.64.11.4830-4833.1996

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Inoculation of mice with the granulocyte-depleting monoclonal antibody RB6-8C5 showed that neutrophils are critical protective effector cells during a Chlamydia trachomatis infection. In addition, administration of monoclonal antibody 2E6 demonstrated that extravasation of neutrophils into the peritoneal cavity in response to inoculation with the C. trachomatis MoPn biovar is dependent on the surface beta-2 integrin molecule CD18.

引用

页码：4830 / 4833

页数：4

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