Interaction of ionic compounds with multilamellar liposomes. An electrokinetic model

被引：9
|
作者：
Molina, F [1 ]
Llacer, C [1 ]
Vila, AO [1 ]
Puchol, A [1 ]
Figueruelo, J [1 ]
机构：
[1] Univ Valencia, Fac Farm, Dept Quim Fis, Burjassot 46100, Valencia, Spain
来源：
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 1998年 / 140卷 / 1-3期
关键词：
biomembrane-ionic compounds interaction; liposomes; zeta-potential;
D O I：
10.1016/S0927-7757(97)00269-0
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
We have proposed a theoretical model of interaction of ionic compounds (ionic adsorbate or ionic drugs), with multilamellar-liposomes, by means of their electrokinetic property variation with the ionic compound concentration. In this work, we show the complete development of the model proposed. Its theoretical results have been analysed to study the influence on the zeta-potential value of the following: number of membranes, size, shear-plane situation, critical concentration of formation (ccf), and the ionic compound concentration which annuls the zeta-potential value of the multilamellar-liposomes formed. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：91 / 101
页数：11
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