Synthesis of 2-thioxoimidazolin-4-one andthiazolo[3,2-a]-benzimidazole derivatives from substituted maleimides

被引：11

作者：

Bentarzi, Yamina ^{[1
,2
]}

Nedjar-Kolli, Bellara ^{[1
]}

Plas, Aurelie ^{[3
]}

Chalard, Pierre ^{[3
]}

Troin, Yves ^{[3
]}

机构：

[1] Univ Sci & Tech Houari Boumediene, Lab Chim Organ Appl, BP 3, Bab Ezzouar 16111, Alger, Algeria

[2] Ctr Rech Sci Tech Analyse Physicochim CRAPC, Alger RP 16004, Algeria

[3] Clermont Univ, ENSCCF, EA 987, LCHG, F-63000 Clermont Ferrand, France

来源：

ARKIVOC | 2010年

关键词：

Thioxoimidazolin-4-one; hetero Michael reaction; thiazolobenzimidazoles; maleimide; PHASE SYNTHESIS;

D O I：

10.3998/ark.5550190.0011.a27

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe here a hetero Michael-type reaction, involving maleimides and 2-cyanoacetichydrazide or 2-mercaptobenzimidazole, followed by an opening cyclization reaction with isothiocyanates. This reaction allows the preparation of new 2-thioxoimidazolidin-4-one and thiazolo[3,2-a]benzimidazole derivatives depending on the nucleophile used.

引用

页码：328 / 337

页数：10

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