Selenium-Based Fluorescence Probes for the Detection of Bioactive Molecules

被引:35
作者
Mamgain, Ritu [1 ]
Singh, Fateh V. [1 ]
机构
[1] Vellore Inst Technol Chennai, Sch Adv Sci SAS, Chem Div, Chennai 600127, Tamil Nadu, India
来源
ACS ORGANIC & INORGANIC AU | 2022年 / 2卷 / 04期
关键词
Organoselenium compounds; Fluorescence probes; ROS; Metal ions; Thiols; GLUTATHIONE-PEROXIDASE MIMICS; OXYGEN SPECIES ROS; SE-N BOND; HYPOCHLOROUS-ACID; ANTIOXIDANT ACTIVITY; REACTIVE OXYGEN; LIVING CELLS; SELECTIVE DETECTION; HYDROGEN-SULFIDE; OXIDATIVE STRESS;
D O I
10.1021/acsorginorgau.1c00047
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Chemistry of organoselenium reagents have now become an important tool of synthetic organic and medicinal chemistry. These reagents activate the olefinic double bonds and used to archive the number of organic transformations under mild reaction conditions. A number of organoselenium compounds have been identified as potent oxidants. Recently, various organoselenium species have been employed as chemical sensors for detecting toxic metals. Moreover, a number of selenium-based fluorescent probes have been developed for detecting harmful peroxides and ROS. In this review article, the synthesis of selenium-based fluorescent probes will be covered including their application in the detection of toxic metals and harmful peroxides including ROS.
引用
收藏
页码:262 / 288
页数:27
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