Structural characterisation and anti-ageing activity of extracellular polysaccharide from a strain of Lachnum sp.

被引:49
|
作者
Ye, Ming [1 ]
Chen, Wu-xi [1 ]
Qiu, Tao [1 ]
Yuan, Ru-yue [1 ]
Ye, Ying-wang [1 ]
Cai, Jing-min [2 ]
机构
[1] Hefei Univ Technol, Coll Biotechnol & Food Engn, Hefei 230009, Peoples R China
[2] Hefei Univ, Dept Biol & Environm Engn, Hefei 230022, Peoples R China
基金
中国国家自然科学基金;
关键词
Lachnum; Exopolysaccharide; Purification; beta(1 -> 3)-D-Glucan; Anti-ageing activity; WATER-SOLUBLE POLYSACCHARIDE; PAPYRACEUM KARST KARST; ANTIMICROBIAL ACTIVITIES; BIOLOGICAL-ACTIVITIES; OXIDATIVE STRESS; PURIFICATION; MICE; METABOLITES; MUSHROOM; RICH;
D O I
10.1016/j.foodchem.2011.10.087
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A homogeneous extracellular polysaccharide of Lachnum YM261(LEPS-1) with a molecular weight of 21670 Da was characterised. According to HPGPC, IR, periodate oxidation and Smith degradation, GC-MS and H-1 NMR analysis, the results indicated that LEPS-1 was a glucan linked by the beta-(1 -> 3)-D-pyran glycosidic bond. The effect of LEPS-1 on anti-ageing in D-gal model mice was also studied. It was found that LEPS-1 significantly increased the activities of antioxidant enzymes (i.e. SOD superoxide dismutase, CAT catalase, GSH-PX glutathione peroxidase) and decreased malondialdehyde (MDA) content in liver, brain and serum of D-gal model mice. These results showed that LEPS-1 had a strong anti-ageing activity. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:338 / 343
页数:6
相关论文
共 50 条
  • [41] Five Sesquiterpenes from Paraconiothyrium sp. and Their Anti-inflammatory Activity
    Zeng, Qingting
    Cui, Hao
    Yao, Houzong
    Yuan, Tao
    CHEMISTRY & BIODIVERSITY, 2023, 20 (06)
  • [42] Structural Elucidation and Anti-Tumor Activity of a Polysaccharide (CP2-S) from Cordyceps militaris Fruit Bodies
    Zhu, Lina
    Wang, Jinyan
    Tang, Qingjiu
    Liu, Yanfang
    POLYMERS, 2024, 16 (14)
  • [43] Structural characterization and anti-alcoholic liver injury activity of a polysaccharide from Coriolus versicolor mycelia
    Wang, Kang-Le
    Lu, Zhen-Ming
    Mao, Xiangjunzhi
    Chen, Lu
    Gong, Jin-Song
    Ren, Yilin
    Geng, Yan
    Li, Heng
    Xu, Hong-Yu
    Xu, Guo-Hua
    Shi, Jin-Song
    Xu, Zheng-Hong
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 137 : 1102 - 1111
  • [44] Characterisation and anti-biofilm activity of extracellular polymeric substances from Oceanobacillus iheyensis
    Kavita, Kumari
    Singh, Vijay Kumar
    Mishra, Avinash
    Jha, Bhavanath
    CARBOHYDRATE POLYMERS, 2014, 101 : 29 - 35
  • [45] Purification and characterization of a novel extracellular carboxylesterase from the moderately halophilic bacterium Thalassobacillus sp. strain DF-E4
    Xiao-Yan Lv
    Li-Zhong Guo
    Lin Song
    Qiang Fu
    Kun Zhao
    Ai-Xia Li
    Xiao-Li Luo
    Wei-Dong Lu
    Annals of Microbiology, 2011, 61 : 281 - 290
  • [46] Structural characteristics and anti-tumor/-oxidant activity in vitro of an acidic polysaccharide from Gynostemma pentaphyllum
    Yu, Shasha
    Yu, Juan
    Dong, Xiaodan
    Li, Shan
    Liu, Anjun
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 161 (161) : 721 - 728
  • [47] Biochemical and Genetic Characterization of an Extracellular Poly(3-Hydroxybutyrate) Depolymerase from Acidovorax Sp. Strain TP4
    Teruyuki Kobayashi
    Akinori Sugiyama
    Yoshiyuki Kawase
    Terumi Saito
    Joris Mergaert
    Jean Swings
    Journal of environmental polymer degradation, 1999, 7 : 9 - 18
  • [48] Anti-Biofilm Activity of Biosurfactant Derived from Halomonas sp., a Lipolytic Marine Bacterium from the Bay of Bengal
    Kayanadath, S.
    Nathan, V. Kumar
    Ammini, P.
    MICROBIOLOGY, 2019, 88 (05) : 585 - 599
  • [49] Structural identification and anti-stomatitis activity of one arabinose-rich polysaccharide from Rehmannia glutinosa
    Li, Meizhu
    Ren, Yunhong
    Lin, Zhiying
    Liu, Lin
    Li, Yanli
    Li, Shuchan
    Guo, Rongxiang
    Li, Pan
    Du, Bing
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 284
  • [50] Anti-inflammatory activity and structural identification of a sulfated polysaccharide CLGP4 from Caulerpa lentillifera
    Sun, Yujiao
    Liu, Zhengqi
    Song, Shuang
    Zhu, Beiwei
    Zhao, Lili
    Jiang, Jinju
    Liu, Ning
    Wang, Jing
    Chen, Xuefeng
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 146 : 931 - 938