Structural characterisation and anti-ageing activity of extracellular polysaccharide from a strain of Lachnum sp.

被引：49
|
作者：
Ye, Ming [1 ]
Chen, Wu-xi [1 ]
Qiu, Tao [1 ]
Yuan, Ru-yue [1 ]
Ye, Ying-wang [1 ]
Cai, Jing-min [2 ]
机构：
[1] Hefei Univ Technol, Coll Biotechnol & Food Engn, Hefei 230009, Peoples R China
[2] Hefei Univ, Dept Biol & Environm Engn, Hefei 230022, Peoples R China
来源：
FOOD CHEMISTRY | 2012年 / 132卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Lachnum; Exopolysaccharide; Purification; beta(1 -> 3)-D-Glucan; Anti-ageing activity; WATER-SOLUBLE POLYSACCHARIDE; PAPYRACEUM KARST KARST; ANTIMICROBIAL ACTIVITIES; BIOLOGICAL-ACTIVITIES; OXIDATIVE STRESS; PURIFICATION; MICE; METABOLITES; MUSHROOM; RICH;
D O I：
10.1016/j.foodchem.2011.10.087
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A homogeneous extracellular polysaccharide of Lachnum YM261(LEPS-1) with a molecular weight of 21670 Da was characterised. According to HPGPC, IR, periodate oxidation and Smith degradation, GC-MS and H-1 NMR analysis, the results indicated that LEPS-1 was a glucan linked by the beta-(1 -> 3)-D-pyran glycosidic bond. The effect of LEPS-1 on anti-ageing in D-gal model mice was also studied. It was found that LEPS-1 significantly increased the activities of antioxidant enzymes (i.e. SOD superoxide dismutase, CAT catalase, GSH-PX glutathione peroxidase) and decreased malondialdehyde (MDA) content in liver, brain and serum of D-gal model mice. These results showed that LEPS-1 had a strong anti-ageing activity. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码：338 / 343
页数：6
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