1998 Alfred Bader Award Lecture - Tangents and targets: The synthetic highway from natural products to medicine

被引：39

作者：

Fallis, AG ^{[1
]}

机构：

[1] Univ Ottawa, Dept Chem, Ottawa Carleton Chem Inst, Ottawa, ON K1N 6N5, Canada

来源：

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1999年 / 77卷 / 02期

关键词：

cycloaddition; taxoids; enediyne; cyclophanes; carbometallation;

D O I：

10.1139/cjc-77-2-159

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthetic studies directed toward various classes of compounds including taxoids and enediyne systems are described. These investigations include tether-controlled imtramolecular Diels-Alder reactions, carbometallation routes to dienes and furans, the use of carbohydrate building blocks, pentadienyl indium reagents for tandem cycloadditions to steroid and triterpenoid skeletons, and the synthesis of taxamycins and revolveneynes and related cyclophanes.

引用

页码：159 / 177

页数：19

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