Investigation of the use of Ge-doped optical fibre for in vitro IMRT prostate dosimetry

被引：23

作者：

Noor, Noramaliza M. ^{[1
]}

Hussein, M. ^{[2
]}

Bradley, D. A. ^{[1
]}

Nisbet, A. ^{[1
,2
]}

机构：

[1] Univ Surrey, Ctr Nucl & Radiat Phys, Dept Phys, Guildford GU2 7XH, Surrey, England

[2] Royal Surrey Cty Hosp NHS Fdn Trust, St Lukes Canc Ctr, Dept Med Phys, Guildford GU2 7XX, Surrey, England

来源：

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2011年 / 652卷 / 01期

关键词：

IMRT; Prostate cancer; Ge-doped optical fibres; TLD-100 and TLD-700; THERMOLUMINESCENCE RESPONSE; PHOTON;

D O I：

10.1016/j.nima.2010.09.085

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

In this study, the thermoluminescence (TL) yield of Ge-doped optical fibres for in vitro dosimetry has been investigated for the verification of Intensity Modulated Radiation Therapy (IMRT) three-dimensional (3D) dose distributions. Ge-doped optical fibres offer many advantages over conventional dosimetry systems including high sensitivity, minimal fading, and cost effectiveness. IMRT verification plans using the Varian Eclipse treatment planning system for two prostate cancer patients were created using Alderson Rando Anthropomorphic Phantom CT data-sets. Measurements were performed using the Rando phantom at nominal energies of 6 MV and 15 MV. Ge-doped optical fibre TL yields were compared with dose determined through use of the treatment planning system and also with the well-established TL lithium fluoride (LiF) dosimetry system (Harshaw TLD-100 and TLD-700). Results show the Ge-doped optical fibre to verify in vitro doses within 3% of the Eclipse predicted doses and LiF TLDs for the particular high energy photon beams used. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：819 / 823

页数：5

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