Sex-specific lean body mass predictive equations are accurate in the obese paediatric population

被引:1
作者
Jackson, Lanier B. [1 ]
Henshaw, Melissa H. [1 ]
Carter, Janet [1 ]
Chowdhury, Shahryar M. [1 ]
机构
[1] Med Univ South Carolina, Div Cardiol, Dept Pediat, 165 Ashley Ave,MSC 915, Charleston, SC 29425 USA
关键词
Lean body mass; obesity; paediatric cardiology; LEFT-VENTRICULAR MASS; FAT MASS; SIZE; CHILDREN; NORMALIZATION; ADOLESCENTS; INDEXATION; ENERGY; ADULTS;
D O I
10.3109/03014460.2015.1069893
中图分类号
Q98 [人类学];
学科分类号
030303 ;
摘要
Background: The clinical assessment of lean body mass (LBM) is challenging in obese children. A sex-specific predictive equation for LBM derived from anthropometric data was recently validated in children. Aim: The purpose of this study was to independently validate these predictive equations in the obese paediatric population. Subjects and methods: Obese subjects aged 4-21 were analysed retrospectively. Predicted LBM (LBMp) was calculated using equations previously developed in children. Measured LBM (LBMm) was derived from dual-energy x-ray absorptiometry. Agreement was expressed as [(LBMm-LBMp)/LBMm] with 95% limits of agreement. Results: Of 310 enrolled patients, 195 (63%) were females. The mean age was 11.83.4 years and mean BMI Z-score was 2.3 +/- 0.4. The average difference between LBMm and LBMp was -0.6% (-17.0%, 15.8%). Pearson's correlation revealed a strong linear relationship between LBMm and LBMp (r=0.97, p<0.01). Conclusion: This study validates the use of these clinically-derived sex-specific LBM predictive equations in the obese paediatric population. Future studies should use these equations to improve the ability to accurately classify LBM in obese children.
引用
收藏
页码:417 / 422
页数:6
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