Exercise and Vascular Insulin Sensitivity in the Skeletal Muscle and Brain

被引：14

作者：

Olver, T. Dylan ^{[1
]}

Laughlin, M. Harold ^{[2
,3
]}

Padilla, Jaume ^{[3
,4
,5
]}

机构：

[1] Univ Saskatchewan, Western Coll Vet Med, Dept Biomed Sci, Saskatoon, SK, Canada

[2] Univ Missouri, Dept Biomed Sci, Room W117,Vet Med Bldg, Columbia, MO 65211 USA

[3] Univ Missouri, Dalton Cardiovasc Res Ctr, Columbia, MO USA

[4] Univ Missouri, Dept Nutr & Exercise Physiol, Columbia, MO USA

[5] Univ Missouri, Dept Child Hlth, Columbia, MO USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2019年 / 47卷 / 02期

基金：

美国国家卫生研究院;

关键词：

vascular insulin signaling; skeletal muscle; brain; physical activity; exercise; blood flow; shear stress; INCREASES BLOOD-FLOW; NITRIC-OXIDE; PHYSICAL-ACTIVITY; INTERVAL SPRINT; RESISTANCE ARTERIES; ENOS CONTENT; STIMULATED VASODILATION; NONUNIFORM INCREASES; MEDIATED DILATION; CORONARY-ARTERY;

D O I：

10.1249/JES.0000000000000182

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

We present the hypothesis that exercise-induced hyperemia, perhaps through vascular shear stress, represents an important factor responsible for the effects of physical activity (PA) on vascular insulin sensitivity. Specifically, we postulate PA involving the greatest amount of skeletal muscle mass and the greatest central neural recruitment maximizes perfusion and consequently enhances vascular insulin sensitivity in the skeletal muscle and brain.

引用

页码：66 / 74

页数：9

共 50 条

[1] Effect of resistance exercise on insulin sensitivity of skeletal muscle
Bo Wang
Xu Luo
Rong-Rong Li
Ya-Na Li
Yu-Chi Zhao
World Journal of Meta-Analysis, 2021, 9 (02) : 101 - 107
[2] Insulin signaling and insulin sensitivity after exercise in human skeletal muscle
Wojtaszewski, JFP
Hansen, BF
Gade, J
Kiens, B
Markuns, JF
Goodyear, LJ
Richter, EA
DIABETES, 2000, 49 (03) : 325 - 331
[3] INCREASED INSULIN SENSITIVITY OF SKELETAL-MUSCLE FOLLOWING EXERCISE
RICHTER, EA
GARETTO, LP
RUDERMAN, NB
DIABETOLOGIA, 1981, 21 (03) : 320 - 320
[4] The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise
Jensen, Jorgen
Rustad, Per Inge
Kolnes, Anders Jensen
Lai, Yu-Chiang
FRONTIERS IN PHYSIOLOGY, 2011, 2
[5] Skeletal muscle phosphatidylcholine and phosphatidylethanolamine respond to exercise and influence insulin sensitivity in men
Lee, Sindre
Norheim, Frode
Gulseth, Hanne L.
Langleite, Torgrim M.
Aker, Andreas
Gundersen, Thomas E.
Holen, Torgeir
Birkeland, Kare I.
Drevon, Christian A.
SCIENTIFIC REPORTS, 2018, 8
[6] Macrophages Are Necessary for Exercise-Induced Enhancement of Insulin Sensitivity in Skeletal Muscle
Ikeda, Shin-ichi
Tamura, Yoshifumi
Kakehi, Saori
Fujitani, Yoshio
Hirose, Takahisa
Kawamori, Ryuzo
Watada, Hirotaka
DIABETES, 2011, 60 : A468 - A468
[7] Skeletal muscle phosphatidylcholine and phosphatidylethanolamine respond to exercise and influence insulin sensitivity in men
Sindre Lee
Frode Norheim
Hanne L. Gulseth
Torgrim M. Langleite
Andreas Aker
Thomas E. Gundersen
Torgeir Holen
Kåre I. Birkeland
Christian A. Drevon
Scientific Reports, 8
[8] Effects of exercise on fatty acid composition in skeletal muscle in relation to insulin sensitivity
Sjodin, A
Andersson, A
Olsson, R
Vessby, B
FASEB JOURNAL, 1997, 11 (03): : 954 - 954
[9] Exercise And/or Metformin Enhances Skeletal Muscle Insulin Sensitivity And Ameliorates Muscle Atrophy In Db/db Mice
Xiang, Mengqi
Yuan, Xinmeng
Zhang, Junlong
Shen, Liting
Liu, Yuting
Lu, Jiao
Zhang, Yuan
MEDICINE & SCIENCE IN SPORTS & EXERCISE, 2023, 55 (09) : 1061 - 1062
[10] The Failure to Improve Insulin Sensitivity by Exercise Is Related to Specific Transcriptional Signatures in Skeletal Muscle
Boehm, Anja
Hoffmann, Christoph
Irmler, Martin
Schnee-Weib, Patrick
Schnauder, Guenter
Sailer, Corinna
Schmid, Vera
Hudemann, Jens
Machann, Juergen
Schick, Fritz
Beckers, Johannes
De Angelis, Martin Hrabe
Staiger, Harald
Fritsche, Andreas
Stefan, Norbert
Niess, Andreas
Haering, Hans-Ulrich
Weigert, Cora
DIABETES, 2016, 65 : A3 - A3

← 1 2 3 4 5 →