Development of a Computerised Antithrombotic Risk Assessment Tool (CARAT) to optimise therapy in older persons with atrial fibrillation

被引:13
作者
Bajorek, Beata V. [1 ,2 ]
Masood, Noman [3 ]
Krass, Ines [4 ]
机构
[1] Univ Technol Sydney, Grad Sch Pharm, Sydney, NSW 2007, Australia
[2] Royal N Shore Hosp, Sydney, NSW, Australia
[3] Wyong Hosp, Dept Pharm, Kanwal, NSW, Australia
[4] Univ Sydney, Fac Pharm A15, Sydney, NSW 2006, Australia
关键词
antithrombotic; atrial fibrillation; decision support; elderly; risk assessment; stroke prevention; CLINICAL CLASSIFICATION SCHEMES; STROKE PREVENTION; PHYSICIAN ATTITUDES; NATIONAL REGISTRY; ANTICOAGULATION; WARFARIN; HEMORRHAGE; MANAGEMENT; IMPACT; AGE;
D O I
10.1111/j.1741-6612.2011.00546.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Aim: To develop and evaluate a novel Computerised Antithrombotic Risk Assessment Tool (CARAT) to aid clinicians' decision making regarding the riskbenefit of antithrombotic therapy in older patients. Methods: CARAT was developed in an iterative process involving multidisciplinary feedback and computerisation of previously trialled algorithms. Hospital-based clinicians then applied the tool to patient cases, to evaluate its usability. Results: Overall, 94% of clinicians (n= 27 yielding 216 responses) were satisfied with CARAT's format. Most (72%) clinician responses agreed with CARAT recommendations; over two-thirds agreed with estimates of stroke and bleeding risk. However, geriatricians were 3.5 times more likely to disagree with CARAT recommendations than cardiologists, particularly in cases of high fall risk. Overall, 63% responded that CARAT was at least somewhat useful for clinical practice; 22% indicating it was very useful. Conclusion: CARAT has potential as a useful decision-support tool to assist clinicians in decision making regarding appropriate antithrombotic therapy in older patients.
引用
收藏
页码:102 / 109
页数:8
相关论文
共 28 条
[11]   Stroke prophylaxis in atrial fibrillation: who gets it and who does not? [J].
Friberg, Leif ;
Hammar, Niklas ;
Ringh, Mattias ;
Pettersson, Hans ;
Rosenqvist, Marten .
EUROPEAN HEART JOURNAL, 2006, 27 (16) :1954-1964
[12]   ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation) Developed in Collaboration With the European Heart Rhythm Association and the Heart Rhythm Society [J].
Fuster, Valentin ;
Ryden, Lars E. ;
Cannom, David S. ;
Crijns, Harry J. ;
Curtis, Anne B. ;
Ellenbogen, Kenneth A. ;
Halperin, Jonathan L. ;
Le Heuzey, Jean-Yves ;
Kay, G. Neal ;
Lowe, James E. ;
Olsson, S. Bertil ;
Prystowsky, Eric N. ;
Tamargo, Juan Luis ;
Wann, Samuel .
CIRCULATION, 2006, 114 (07) :E257-E354
[13]   Clinical classification schemes for predicting hemorrhage: Results from the National Registry of Atrial Fibrillation (NRAF) [J].
Gage, BF ;
Yan, Y ;
Milligan, PE ;
Waterman, AD ;
Culverhouse, R ;
Rich, MW ;
Radford, MJ .
AMERICAN HEART JOURNAL, 2006, 151 (03) :713-719
[14]   Validation of clinical classification schemes for predicting stroke - Results from the national registry of Atrial Fibrillation [J].
Gage, BF ;
Waterman, AD ;
Shannon, W ;
Boechler, M ;
Rich, MW ;
Radford, MJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (22) :2864-2870
[15]  
Garvin R, 2006, J FAM PRACTICE, V55, P157
[16]   Prevalence of diagnosed atrial fibrillation in adults - National implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) study [J].
Go, AS ;
Hylek, EM ;
Phillips, KA ;
Chang, YC ;
Henault, LE ;
Selby, JV ;
Singer, DE .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (18) :2370-2375
[17]   Implications of stroke risk criteria on the anticoagulation decision in nonvalvular atrial fibrillation - The anticoagulation and risk factors in atrial fibrillation (ATRIA) study [J].
Go, AS ;
Hylek, EM ;
Phillips, KA ;
Borowsky, LH ;
Henault, LE ;
Chang, YC ;
Selby, JV ;
Singer, DE .
CIRCULATION, 2000, 102 (01) :11-13
[18]  
Hankey GJ, 2001, MED J AUSTRALIA, V174, P234
[19]   Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: A meta-analysis [J].
Hart, RG ;
Benavente, O ;
McBride, R ;
Pearce, LA .
ANNALS OF INTERNAL MEDICINE, 1999, 131 (07) :492-+
[20]  
KOUDSTAAL PJ, 1995, NEW ENGL J MED, V333, P5