Genetic, biochemical and structural approaches to talin function

被引：36
作者：
Critchley, DR [1 ]
机构：
[1] Univ Leicester, Dept Biochem, Leicester LE1 7RH, Leics, England
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 2005年 / 33卷
关键词：
actin cytoskeleton; integrin; talin; vinculin-binding site;
D O I：
10.1042/BST0331308
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The cytoskeletal protein talin plays a key role in coupling the integrin family of cell adhesion molecules to the actin cytoskeleton. in this paper I present a brief review on talin and summarize our recent studies, in which we have taken both genetic and structural approaches to further elucidate the function of the protein.
引用
收藏
页码：1308 / 1312
页数：5
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