Charged particles in radiotherapy: A 5-year update of a systematic review

被引:82
作者
De Ruysscher, Dirk [1 ]
Lodge, M. Mark [2 ]
Jones, Bleddyn [3 ]
Brada, Michael [4 ]
Munro, Alastair [5 ]
Jefferson, Thomas
Pijls-Johannesma, Madelon [1 ]
机构
[1] Maastricht Univ, Med Ctr, Dept Radiat Oncol MAASTRO, Maastricht, Netherlands
[2] Int Network Canc Treatment & Res, Oxford, England
[3] Univ Oxford, Gray Inst Radiat Oncol & Biol, Oxford OX1 2JD, England
[4] Inst Canc Res, Sutton, Surrey, England
[5] Univ Dundee, Dept Radiotherapy, Dundee DD1 4HN, Scotland
关键词
Proton therapy; Charged particles; Radiotherapy; PROTON-BEAM THERAPY; RANDOMIZED CLINICAL-TRIALS; MODULATED ARC THERAPY; CELL-LUNG-CANCER; COST-EFFECTIVENESS; RADIATION-THERAPY; BREAST-CANCER; IRRADIATION; TUMORS;
D O I
10.1016/j.radonc.2012.01.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although proton therapy has been used for many decades because of their superior dose distribution over photons and reduced integral dose, their clinical implementation is still controversial. We updated a systematic review of charged particle therapy. Although still no randomised trials were identified, the field is moving quickly and we therefore also formulated ways to move forward. In our view, the aim should be to build enough proton therapy facilities with interest in research to further improve the treatment and to run the needed clinical trials. (C) 2012 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 103 (2012) 5-7
引用
收藏
页码:5 / 7
页数:3
相关论文
共 42 条
[41]   Irradiation with protons for the individualized treatment of patients with locally advanced rectal cancer: A planning study with clinical implications [J].
Wolff, Hendrik Andreas ;
Wagner, Daniela Melanie ;
Conradi, Lena-Christin ;
Hennies, Steffen ;
Ghadimi, Michael ;
Hess, Clemens Friedrich ;
Christiansen, Hans .
RADIOTHERAPY AND ONCOLOGY, 2012, 102 (01) :30-37
[42]   Technology Evolution: Is It Survival of the Fittest? [J].
Zietman, Anthony ;
Goitein, Michael ;
Tepper, Joel E. .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (27) :4275-4279