Charged particles in radiotherapy: A 5-year update of a systematic review

被引:82
作者
De Ruysscher, Dirk [1 ]
Lodge, M. Mark [2 ]
Jones, Bleddyn [3 ]
Brada, Michael [4 ]
Munro, Alastair [5 ]
Jefferson, Thomas
Pijls-Johannesma, Madelon [1 ]
机构
[1] Maastricht Univ, Med Ctr, Dept Radiat Oncol MAASTRO, Maastricht, Netherlands
[2] Int Network Canc Treatment & Res, Oxford, England
[3] Univ Oxford, Gray Inst Radiat Oncol & Biol, Oxford OX1 2JD, England
[4] Inst Canc Res, Sutton, Surrey, England
[5] Univ Dundee, Dept Radiotherapy, Dundee DD1 4HN, Scotland
关键词
Proton therapy; Charged particles; Radiotherapy; PROTON-BEAM THERAPY; RANDOMIZED CLINICAL-TRIALS; MODULATED ARC THERAPY; CELL-LUNG-CANCER; COST-EFFECTIVENESS; RADIATION-THERAPY; BREAST-CANCER; IRRADIATION; TUMORS;
D O I
10.1016/j.radonc.2012.01.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although proton therapy has been used for many decades because of their superior dose distribution over photons and reduced integral dose, their clinical implementation is still controversial. We updated a systematic review of charged particle therapy. Although still no randomised trials were identified, the field is moving quickly and we therefore also formulated ways to move forward. In our view, the aim should be to build enough proton therapy facilities with interest in research to further improve the treatment and to run the needed clinical trials. (C) 2012 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 103 (2012) 5-7
引用
收藏
页码:5 / 7
页数:3
相关论文
共 42 条
[1]  
Advisory Group on Ionising Radiation, CIRC DIS RISK
[2]   Comparison of second cancer risk due to out-of-field doses from 6-MV IMRT and proton therapy based on 6 pediatric patient treatment plans [J].
Athar, Basit S. ;
Paganetti, Harald .
RADIOTHERAPY AND ONCOLOGY, 2011, 98 (01) :87-92
[3]   Randomized controlled trials in health technology assessment: Overkill or overdue? [J].
Bentzen, Soren M. .
RADIOTHERAPY AND ONCOLOGY, 2008, 86 (02) :142-147
[4]   Proton therapy in clinical practice: Current clinical evidence [J].
Brada, Michael ;
Pijls-Johannesma, Madelon ;
De Ruysscher, Dirk .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (08) :965-970
[5]   Current Clinical Evidence for Proton Therapy [J].
Brada, Michael ;
Pijls-Johannesma, Madelon ;
De Ruysscher, Dirk .
CANCER JOURNAL, 2009, 15 (04) :319-324
[6]   The superiority of hybrid-volumetric arc therapy (VMAT) technique over double arcs VMAT and 3D-conformal technique in the treatment of locally advanced non-small cell lung cancer - A planning study [J].
Chan, Oscar S. H. ;
Lee, Michael C. H. ;
Hung, Albert W. M. ;
Chang, Amy T. Y. ;
Yeung, Rebecca M. W. ;
Lee, Anne W. M. .
RADIOTHERAPY AND ONCOLOGY, 2011, 101 (02) :298-302
[7]   Particle therapy at the Heidelberg Ion Therapy Center (HIT) - Integrated research-driven university-hospital-based radiation oncology service in Heidelberg, Germany [J].
Combs, Stephanie E. ;
Jaekel, Oliver ;
Haberer, Thomas ;
Debus, Juergen .
RADIOTHERAPY AND ONCOLOGY, 2010, 95 (01) :41-44
[8]   Cranio-spinal irradiation with volumetric modulated arc therapy: A multi-institutional treatment experience [J].
Fogliata, Antonella ;
Bergstrom, Stefan ;
Cafaro, Ines ;
Clivio, Alessandro ;
Cozzi, Luca ;
Dipasquale, Giovanna ;
Hallstrom, Per ;
Mancosu, Pietro ;
Navarria, Piera ;
Nicolini, Giorgia ;
Parietti, Emanuela ;
Pesce, Gianfranco A. ;
Richetti, Antonella ;
Scorsetti, Marta ;
Vanetti, Eugenio ;
Weber, Damien C. .
RADIOTHERAPY AND ONCOLOGY, 2011, 99 (01) :79-85
[9]   Should randomized clinical trials be required for proton radiotherapy? An alternative view [J].
Glatstein, Eli ;
Glick, John ;
Kaiser, Larry ;
Hahn, Stephen M. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (15) :2438-2439
[10]   Proton beam therapy - Do we need the randomised trials and can we do them? [J].
Glimelius, Bengt ;
Montelius, Anders .
RADIOTHERAPY AND ONCOLOGY, 2007, 83 (02) :105-109