Values of the Minimal Clinically Important Difference for the Neuropsychiatric Inventory Questionnaire in Individuals with Dementia

被引：30
作者：
Mao, Hui-Fen [1 ]
Kuo, Chun-An [1 ]
Huang, Wen-Ni [2 ]
Cummings, Jeffrey L. [3 ]
Hwang, Tzung-Jeng [4 ,5 ]
机构：
[1] Natl Taiwan Univ, Coll Med, Sch Occupat Therapy, Taipei 10764, Taiwan
[2] I Shou Univ, Dept Phys Therapy, Kaohsiung, Taiwan
[3] Cleveland Clin, Las Vegas, NV USA
[4] Natl Taiwan Univ Hosp, Dept Psychiat, Taipei 100, Taiwan
[5] Natl Taiwan Univ, Coll Med, Taipei 10764, Taiwan
来源：
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY | 2015年 / 63卷 / 07期
关键词：
behavioral and psychological symptoms of dementia (BPSDs); dementia; minimal clinically important difference; Neuropsychiatric Inventory Questionnaire (NPI-Q); LOW-BACK-PAIN; NPI-Q; HEALTH-STATUS; SYMPTOMS; FORM; RELIABILITY; PREVALENCE; VALIDATION; TRIALS;
D O I：
10.1111/jgs.13473
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
ObjectivesTo estimate the minimal clinically important difference (MCID) for the Neuropsychiatric Inventory Questionnaire (NPI-Q), a widely used measure of behavioral and psychological symptoms of dementia (BPSDs) and associated caregiver stress. DesignTen registered nurses rated the severity of BPSDs and caregiver distress using the NPI-Q during six monthly assessments and an external reference, a 7-point Likert-type global rating of BPSDs change during five monthly assessments from the second to the sixth month. An anchor-based (global ratings of change) approach and a distribution-based (standard error of measurement) approach were used to determine the MCID for the NPI-Q severity and distress subscales. SettingLong-term care facility. ParticipantsNonbedridden residents with dementia (n=45) and registered nurses (n=10). MeasurementsNPI-Q (severity and caregiver distress subscales) and global ratings of changes in BPSDs on a 7-point Likert-type scale. ResultsThe NPI-Q MCID ranges were 2.77 to 3.18 for severity and 3.10 to 3.95 for distress. Residents in the highest NPI-Q tertile at baseline had higher MCID severity (3.62) and distress (5.08) scores than those in the lowest tertile (severity (2.40), distress (3.10)). ConclusionThis study provides an estimate of the MCID for severity and distress subscales of the NPI-Q, which can help clinicians and researchers determine whether NPI-Q change scores within a group of individuals with dementia are beyond measurement error and are clinically important.
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收藏
页码：1448 / 1452
页数：5
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