Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives

被引：62

作者：

Bar-Nur, Ori ^{[1
]}

Caspi, Inbal ^{[1
]}

Benvenisty, Nissim ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Dept Genet, Stem Cell Unit, Inst Life Sci, IL-91904 Jerusalem, Israel

来源：

JOURNAL OF MOLECULAR CELL BIOLOGY | 2012年 / 4卷 / 03期

关键词：

D O I：

10.1093/jmcb/mjs007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：180 / 183

页数：4

共 12 条

[1] Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation
Brouwer, J. R.
Mientjes, E. J.
Bakkera, C. E.
Nieuwenhuizen, I. M.
Seuerijnen, L. A.
Van der Linde, H. C.
Nelson, D. L.
Oostra, B. A.
Willemsen, R.
[J]. EXPERIMENTAL CELL RESEARCH, 2007, 313 (02) : 244 - 253
[2] Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells
Coffee, B
Zhang, FP
Warren, ST
Reines, D
[J]. NATURE GENETICS, 1999, 22 (01) : 98 - 101
[3] FMR1 and the fragile X syndrome:: Human genome epidemiology review
Crawford, DC
Acuña, JM
Sherman, SL
[J]. GENETICS IN MEDICINE, 2001, 3 (05) : 359 - 371
[4] Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum Disorders
De Rubeis, Silvia
Bagni, Claudia
[J]. JOURNAL OF NEURODEVELOPMENTAL DISORDERS, 2011, 3 (03) : 257 - 269
[5] Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos
Eiges, Rachel
Urbach, Achia
Malcov, Mira
Frumkin, Tsvia
Schwartz, Tamar
Amit, Ami
Yaron, Yuval
Eden, Amir
Yanuka, Ofra
Benvenisty, Nissim
Ben-Yosef, Dalit
[J]. CELL STEM CELL, 2007, 1 (05) : 568 - 577
[6] A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
Marchetto, Maria C. N.
Carromeu, Cassiano
Acab, Allan
Yu, Diana
Yeo, Gene W.
Mu, Yangling
Chen, Gong
Gage, Fred H.
Muotri, Alysson R.
[J]. CELL, 2010, 143 (04) : 527 - 539
[7] Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies
Rudek, MA
Zhao, M
He, P
Hartke, C
Gilbert, J
Gore, SD
Carducci, MA
Baker, SD
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (17) : 3906 - 3911
[8] Induced neuronal differentiation of human embryonic stem cells
Schuldiner, M
Eiges, R
Eden, A
Yanuka, O
Itskovitz-Eldor, J
Goldstein, RS
Benvenisty, N
[J]. BRAIN RESEARCH, 2001, 913 (02) : 201 - 205
[9] Sutcliffe James S., 1992, Human Molecular Genetics, V1, P397, DOI 10.1093/hmg/1.6.397
[10] Differential Modeling of Fragile X Syndrome by Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
Urbach, Achia
Bar-Nur, Ori
Daley, George Q.
Benvenisty, Nissim
[J]. CELL STEM CELL, 2010, 6 (05) : 407 - 411

← 1 2 →