On the mechanism of long-range electron transfer through DNA

被引：0

作者：

Giese, B

Wessely, S

Spormann, M

Lindemann, U

Meggers, E

Michel-Beyerle, ME

机构：

[1] Univ Basel, Dept Chem, CH-4056 Basel, Switzerland

[2] Tech Univ Munich, Inst Phys & Theoret Chem, D-85748 Garching, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1999年 / 38卷 / 07期

关键词：

bioorganic chemistry; DNA oxidation; electron transfer; radicals;

D O I：

10.1002/(SICI)1521-3773(19990401)38:7<996::AID-ANIE996>3.0.CO;2-4

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Hopping between bases of similar redox potentials is the mechanism by which charge transport occurs through DNA. This was shown by rate measurements performed with double strands 1-3. This mechanism explains why hole transfer displays a strong sequence dependence, and postulates that electron transfer in unperturbed DNA should not be dependent on the sequence.

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页码：996 / 998

页数：3

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