Two new lactones from whole herbs of Patrinia villosa Juss

被引：5

作者：

Bai, Ming ^{[1
]}

Liu, Si-Fan ^{[1
]}

Wang, Wei ^{[1
]}

Wang, Xiao-Bo ^{[2
]}

Huang, Xiao-Xiao ^{[1
,2
]}

Song, Shao-Jiang ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Sch Tradit Chinese Mat Med, Shenyang 110016, Liaoning, Peoples R China

[2] Chinese Peoples Liberat Army 210 Hosp, Dalian 116021, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2017年 / 22卷

关键词：

Patrinia villosa Juss; Lactones; Cytotoxicity; Antimicrobial; CONSTITUENTS; ANTIOXIDANT; EXTRACTION; PLANTS;

D O I：

10.1016/j.phytol.2017.09.021

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chemical investigation of 70% EtOH exact of Patrinia villosa Juss. led to the isolation, purification and identification of two new lactones (1-2) along with twelve known compounds (3-14). Their structures were established by comprehensive spectroscopic analyses. All compounds were evaluated for their cytotoxic activities against A549, HepG2, Hep3 B and MCF-7 cancer cell lines. Compounds 1, 8, 10, 11 and 12 displayed weak cytotoxic activities against MCF-7 cell line. In addition, compounds 1, 2, 8, 10, 11 and 12 were also tested their antimicrobial activities against Micrococcus luteus. Unfortunately, these compounds were found to be inactive.

引用

页码：145 / 148

页数：4

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