Dye-conjugated upconversion nanoparticles for ratiometric imaging of intracellular pH values

被引：55

作者：

Ma, Tingchun ^{[1
,2
]}

Ma, Yun ^{[1
,2
]}

Liu, Shujuan ^{[1
,2
]}

Zhang, Lili ^{[1
,2
]}

Yang, Tianshe ^{[1
,2
]}

Yang, Hui-Ran ^{[1
,2
]}

Lv, Wen ^{[1
,2
]}

Yu, Qi ^{[1
,2
]}

Xu, Wenjuan ^{[1
,2
]}

Zhao, Qiang ^{[1
,2
]}

Huang, Wei ^{[1
,2
,3
,4
]}

机构：

[1] NUPT, Key Lab Organ Elect & Informat Displays, Natl Jiangsu Synerget Innovat Ctr Adv Mat SICAM, Nanjing 210023, Jiangsu, Peoples R China

[2] NUPT, Inst Adv Mat, Natl Jiangsu Synerget Innovat Ctr Adv Mat SICAM, Nanjing 210023, Jiangsu, Peoples R China

[3] Nanjing Tech Univ NanjingTech, Key Lab Flexible Elect KLOFE, Natl Jiangsu Synerget Innovat Ctr Adv Mat SICAM, Nanjing 211816, Jiangsu, Peoples R China

[4] Nanjing Tech Univ NanjingTech, IAM, Natl Jiangsu Synerget Innovat Ctr Adv Mat SICAM, Nanjing 211816, Jiangsu, Peoples R China

来源：

JOURNAL OF MATERIALS CHEMISTRY C | 2015年 / 3卷 / 26期

基金：

中国国家自然科学基金;

关键词：

ANTICANCER DRUG-DELIVERY; IN-VIVO; UPCONVERTING NANOPARTICLES; MESOPOROUS SILICA; CYANIDE ANIONS; CELLS; NANOCRYSTALS; NANOSYSTEM; THERAPY; VITRO;

D O I：

10.1039/c5tc00849b

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A ratiometric pH probe based on Tm3+ doped UCNPs functionalized with dye xylenol orange on the surface was developed, which can realize ratiometric pH sensing and imaging under continuous-wave excitation at 980 nm through the quenching and recovery of upconversion luminescence at 450 nm from UCNPs.

引用

页码：6616 / 6620

页数：5

共 39 条

[1] Luminescent Sensing of Oxygen Using a Quenchable Probe and Upconverting Nanoparticles [J].

Achatz, Daniela E. ;

Meier, Robert J. ;

Fischer, Lorenz H. ;

Wolfbeis, Otto S. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (01) :260-263

[2] Induced self-assembly and disassembly of water-soluble alkynylplatinum(II) terpyridyl complexes with "switchable" near-infrared (NIR) emission modulated by metal-metal interactions over physiological pH: demonstration of pH-responsive NIR luminescent probes in cell-imaging studies [J].

Chung, Clive Yik-Sham ;

Li, Steve Po-Yam ;

Louie, Man-Wai ;

Lo, Kenneth Kam-Wing ;

Yam, Vivian Wing-Wah .

CHEMICAL SCIENCE, 2013, 4 (06) :2453-2462

[3] Hydrophobic Anticancer Drug Delivery by a 980 nm Laser-Driven Photothermal Vehicle for Efficient Synergistic Therapy of Cancer Cells In Vivo [J].

Dong, Kai ;

Liu, Zhen ;

Li, Zhenhua ;

Ren, Jinsong ;

Qu, Xiaogang .

ADVANCED MATERIALS, 2013, 25 (32) :4452-4458

[4] Regulates calcium release kinetics in sarcoplasmic reticulum vesicles [J].

Donoso, P ;

Beltran, M ;

Hidalgo, C .

BIOCHEMISTRY, 1996, 35 (41) :13419-13425

[5] Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells [J].

Fan, Li ;

Fu, Yue-Jun ;

Liu, Qiao-Ling ;

Lu, Dong-Tao ;

Dong, Chuan ;

Shuang, Shao-Min .

CHEMICAL COMMUNICATIONS, 2012, 48 (91) :11202-11204

[6] Spatially and functionally distinct Ca2+ stores in sarcoplasmic and endoplasmic reticulum [J].

Golovina, VA ;

Blaustein, MP .

SCIENCE, 1997, 275 (5306) :1643-1648

[7] Fluorescent Indicators for Intracellular pH [J].

Han, Junyan ;

Burgess, Kevin .

CHEMICAL REVIEWS, 2010, 110 (05) :2709-2728

[8] Optimized pH-responsive cyanine fluorochromes for detection of acidic environments [J].

Hilderbrand, Scott A. ;

Weissleder, Ralph .

CHEMICAL COMMUNICATIONS, 2007, (26) :2747-2749

[9] Biocompatibility of silica coated NaYF4 upconversion fluorescent nanocrystals [J].

Jalil, Rufaihah Abdul ;

Zhang, Yong .

BIOMATERIALS, 2008, 29 (30) :4122-4128

[10] Carbon Dot-Based Inorganic-Organic Nanosystem for Two-Photon Imaging and Biosensing of pH Variation in Living Cells and Tissues [J].

Kong, Biao ;

Zhu, Anwei ;

Ding, Changqin ;

Zhao, Xiaoming ;

Li, Bo ;

Tian, Yang .

ADVANCED MATERIALS, 2012, 24 (43) :5844-5848

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