Complexation of biologically active amines by a water-soluble calix[5]arene A nanocalorimetric investigation

被引：26

作者：

Arena, Giuseppe ^{[1
]}

Pappalardo, Andrea ^{[1
]}

Pappalardo, Sebastiano ^{[1
]}

Gattuso, Giuseppe ^{[2
]}

Notti, Anna ^{[2
]}

Parisi, Melchiorre F. ^{[2
]}

Pisagatti, Ilenia ^{[2
]}

Sgarlata, Carmelo ^{[1
]}

机构：

[1] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy

[2] Univ Messina, Dipartimento Sci Chim, I-98166 Messina, Italy

来源：

JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY | 2015年 / 121卷 / 03期

关键词：

Water-soluble calixarenes; Neurotransmitters; Trace amines; Host-guest complexes; Nano-ITC; Driving forces; ISOTHERMAL TITRATION CALORIMETRY; VANT-HOFF; SIGNIFICANT DISCREPANCIES; THERMODYNAMICS; ENTHALPIES; RECOGNITION; SULFONATOCALIXARENES; NEUROTRANSMITTERS; ASSOCIATION; RECEPTORS;

D O I：

10.1007/s10973-015-4522-3

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

Host-guest complexes of an amphiphilic water-soluble p-tert-butylcalix[5]arene bearing 4-sulphonatobutoxy groups at the narrow rim with trace amines (2-phenylethylamine and tyramine) and a neurotransmitter (dopamine), originally investigated via H-1 NMR, have been re-examined via ITC in order to double check the reliability of the values obtained through a van't Hoff analysis of the NMR data. The calorimetrically determined data confirm the existence of a 1:1 host-guest species; however, there are inconsistencies between the van't Hoff derived values and the values determined via direct calorimetry. These discrepancies do not result from proton displacement due to inclusion, but rather result from the temperature dependence of the van't Hoff enthalpies.

引用

页码：1073 / 1079

页数：7

共 44 条

[1] Water-soluble pentasulfonatocalix[5]arene: selective recognition of ditopic trimethylammonium cations by a triple non-covalent interaction [J].