Protein kinase Cδ

被引：219
作者：
Gschwendt, M [1 ]
机构：
[1] German Canc Res Ctr, D-69120 Heidelberg, Germany
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1999年 / 259卷 / 03期
关键词：
protein kinase C delta; activation; autophosphorylation; down-regulation; structure; tyrosine phosphorylation; function;
D O I：
10.1046/j.1432-1327.1999.00120.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The protein kinase C (PKC) family consists of 11 isoenzymes that, due to structural and enzymatic differences, can be subdivided into three groups: The Ca2+-dependent, diacylglycerol (DAG)-activated cPKCs (conventional PKCs: alpha, beta(1), beta(2), gamma); the Ca2+-independent, DAG-activated nPKCs (novel PKCs: delta, epsilon, eta, theta, mu), and the Ca2+-dependent, DAG non-responsive aPKCs (atypical PKCs: zeta, lambda iota). PKC mu is a novel PKC, but with some special structural and enzymatic properties.
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收藏
页码：555 / 564
页数：10
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