Endothelial Cells Don't Waste: Endothelial-Derived Lactate Boosts Muscle Regeneration

被引：2

作者：

Castro, Marco ^{[1
]}

Andrade, Jorge ^{[1
]}

Potente, Michael ^{[1
,2
]}

机构：

[1] Max Planck Inst Heart & Lung Res, Angiogenesis & Metab Lab, D-61231 Bad Nauheim, Germany

[2] DZHK German Ctr Cardiovasc Res, Partner Site Frankfurt Rhine Main, D-13347 Berlin, Germany

来源：

DEVELOPMENTAL CELL | 2020年 / 54卷 / 02期

关键词：

D O I：

10.1016/j.devcel.2020.06.023

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Blood vessels are an essential interface between the circulation and tissue that deploy signaling molecules (angiocrines) for organ development, homeostasis, and repair. In a recent issue of Cell Metabolism, Zhang et al. (2020) identify lactate as an endothelial-derived signal promoting ischemic muscle regeneration, establishing metabolites as a new angiocrine class.

引用

页码：137 / 139

页数：3

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