Longevity hits a roadblock

被引:37
作者
Lombard, David B. [1 ,2 ]
Pletcher, Scott D. [2 ,3 ]
机构
[1] Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Inst Gerontol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Mol & Integrat Physiol, Ann Arbor, MI 48109 USA
关键词
D O I
10.1038/477410a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Increased expression of sirtuin proteins has been shown to enhance lifespan in several organisms. New data indicate that some of the reported effects may have been due to confounding factors in experimental design. Here, experts discuss the significance of these data for research into ageing. See Letter p.482
引用
收藏
页码:410 / 410
页数:1
相关论文
共 19 条
[1]  
Tissenbaum HA(2001)undefined Nature 410 227-230
[2]  
Guarente L(2004)undefined Proc. Natl Acad. Sci. USA 101 15998-16003
[3]  
Rogina B(2009)undefined Trends Endocrinol. Metab. 20 325-331
[4]  
Helfand SL(2009)undefined Aging 1 38-48
[5]  
Cantó C(2011)undefined Nature 477 482-485
[6]  
Auwerx J(2011)undefined N. Engl. J. Med. 364 2235-2244
[7]  
Bauer JH(2011)undefined PLoS Genet. 7 e1002235-350
[8]  
Burnett C(2005)undefined Nature Genet. 37 349-140
[9]  
Guarente L(2010)undefined Nature Commun. 1 3-823
[10]  
Rizki G(2007)undefined Ageing Res. Rev. 6 128-1122