The basophil activation test in the diagnosis of anaesthesia-related allergy

被引：2
作者：
Ebo, D. G. [1 ]
机构：
[1] Univ Antwerp, Univ Antwerp Hosp, Dept Immunol Allergol Rheumatol, B-2610 Antwerp, Belgium
来源：
REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE | 2008年 / 48卷 / 03期
关键词：
allergy; anesthesia; flow cytometric; latex; basophil activation test (BAT);
D O I：
10.1016/j.allerg.2008.01.003
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
This review intends to summarise on the application of the basophil activation test (BAT) in the diagnostic management of anaesthesia-related allergy. The BAT relies upon flow cytometric quantification of alterations of particular basophilic activation markers. In the context of anaesthesia-related allergy the technique has been applied and proven reliable to diagnose IgE-mediated allergy from drugs (e.g., neuromuscular blocking agents, beta-lactam antibiotics), natural rubber latex, chlorhexidine, plasma expanders and dyes. Moreover, the technique has proven to be complementary to skin tests in the assessment of cross-reactivity and tailoring safe alternative regimens for future anaesthesia. (c) 2008 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：214 / 216
页数：3
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