Keeping It Real: Antibiotic Use Problems and Stewardship Solutions in Low- and Middle-income Countries

被引：17

作者：

Basu, Saurav ^{[1
]}

Copana, Raul ^{[2
,3
]}

Morales, Ronaldo ^{[4
]}

Anugulruengkitt, Suvaporn ^{[5
,6
]}

Puthanakit, Thanyawee ^{[5
,6
]}

Maramba-Lazarte, Cecilia ^{[7
,8
]}

Williams, Phoebe ^{[9
,10
]}

Musembi, John ^{[10
]}

Boga, Mwanamvua ^{[10
]}

Issack, Mohammad ^{[11
]}

Hokororo, Adolfine ^{[12
]}

Falade, Adegoke G. ^{[13
,14
]}

Trehan, Indi ^{[15
,16
,17
]}

Molyneux, Elizabeth ^{[18
]}

Arscott-Mills, Tonya ^{[19
]}

Alemayehu, Tinsae ^{[20
,21
]}

Bryant, Penelope A. ^{[22
,23
,24
]}

机构：

[1] Maulana Azad Med Coll, Dept Community Med, New Delhi, India

[2] San Simon Univ, Fac Med, Dept Pediat, Cochabamba, Bolivia

[3] Manuel A Villarroel Childrens Hosp, Intens Care Unit, Cochabamba, Bolivia

[4] Univ Sao Paulo, Sch Pharmaceut Sci, Clin Pharmacokinet Ctr, Sao Paulo, Brazil

[5] Chulalongkorn Univ, Fac Med, Dept Pediat, Bangkok, Thailand

[6] Chulalongkorn Univ, Fac Med, Ctr Excellence Pediat Infect Dis & Vaccines, Bangkok, Thailand

[7] Univ Philippines, Dept Pediat, Coll Med, Philippine Gen Hosp,Div Infect & Trop Dis INTROP, Manila, Philippines

[8] Univ Philippines, Coll Med, Dept Pharmacol & Toxicol, Manila, Philippines

[9] Kenya Govt Med Res Ctr, KEMRI Wellcome Trust Res Programme, Dept Paediat, Kilifi, Kenya

[10] Univ Sydney, Fac Med, Sch Publ Hlth, Sydney, NSW, Australia

[11] Victoria Hosp, Bacteriol Dept, Cent Hlth Lab, Quatre Bornes, Mauritius

[12] Catholic Univ Hlth & Allied Sci Bugando, Dept Paediat & Child Hlth, Mwanza, Tanzania

[13] Univ Ibadan, Coll Med, Dept Paediat, Ibadan, Nigeria

[14] Univ Coll Hosp, Ibadan, Nigeria

[15] Univ Washington, Dept Pediat, Seattle, WA 98195 USA

[16] Univ Washington, Dept Global Hlth, Seattle, WA 98195 USA

[17] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

[18] Coll Med Blantyre, Paediat & Child Hlth Dept, Blantyre, Malawi

[19] Botswana UPenn Partnership, Gaborone, Botswana

[20] Amer Med Ctr, Addis Ababa, Ethiopia

[21] St Pauls Hosp, Dept Infect Dis & Travel Med, Millennium Med Coll, Addis Ababa, Ethiopia

[22] Royal Childrens Hosp, Hosp In The Home, Parkville, Vic, Australia

[23] Murdoch Childrens Res Inst, Clin Paediat, Parkville, Vic, Australia

[24] Univ Melbourne Parkville, Dept Paediat, Parkville, Vic, Australia

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2022年 / 41卷 / 3S期

关键词：

antibiotic resistance; antimicrobial stewardship; pediatric infectious diseases; LMIC; PRESCRIPTION; CHILDREN; PHILIPPINES; PREVALENCE; PNEUMONIA;

D O I：

10.1097/INF.0000000000003321

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Antimicrobial resistance is a global health threat and there is an urgent need to manage antibiotic use to slow its development. However, antimicrobial stewardship interventions in low- and middle-income countries (LMIC) have been limited in terms of their resourcing, feasibility and effectiveness in the face of greater challenges in child mortality. We sought to gather together examples of antibiotic use problems faced by clinicians in LMIC, many of which are unique to these settings, and real-world antimicrobial stewardship solutions identified, with the goal of learning broader lessons that might be applicable across LMIC.

引用

页码：S18 / S25

页数：8

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