Multiplexed fluorescence in situ hybridization-based detection of circulating tumor cells: A novel liquid-based technology to facilitate accurate and early identification of non-small cell lung cancer patients

被引:3
作者
Zhu, Yili [1 ]
Lowe, Alarice Cheng-Yi [1 ]
机构
[1] Stanford Univ, Dept Pathol, Stanford, CA 94305 USA
关键词
CTCs; FISH; indeterminate lung nodules; lung cancer; NSCLC; DIAGNOSIS;
D O I
10.1002/cncy.22277
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Multiplexed fluorescence in situ hybridization-based circulating tumor cell (CTC) technology detects cytogenetic abnormalities in patients who are at risk for non-small cell lung cancer with high accuracy. Combined with low-dose computed tomography, this CTC technology can efficiently rule out malignancy in at-risk patients with benign pulmonary nodules.
引用
收藏
页码:518 / 519
页数:2
相关论文
共 12 条
[1]   Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening [J].
Aberle, Denise R. ;
Adams, Amanda M. ;
Berg, Christine D. ;
Black, William C. ;
Clapp, Jonathan D. ;
Fagerstrom, Richard M. ;
Gareen, Ilana F. ;
Gatsonis, Constantine ;
Marcus, Pamela M. ;
Sicks, JoRean D. .
NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) :395-409
[2]   Symptoms and the early diagnosis of lung cancer [J].
Birring, SS ;
Peake, MD .
THORAX, 2005, 60 (04) :268-269
[3]   Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer [J].
de Bono, Johann S. ;
Scher, Howard I. ;
Montgomery, R. Bruce ;
Parker, Christopher ;
Miller, M. Craig ;
Tissing, Henk ;
Doyle, Gerald V. ;
Terstappen, Leon W. W. M. ;
Pienta, Kenneth J. ;
Raghavan, Derek .
CLINICAL CANCER RESEARCH, 2008, 14 (19) :6302-6309
[4]  
Fehm T, 2002, CLIN CANCER RES, V8, P2073
[5]   Circulating tumor cell technologies [J].
Ferreira, Meghaan M. ;
Romani, Vishnu C. ;
Jeffrey, Stefanie S. .
MOLECULAR ONCOLOGY, 2016, 10 (03) :374-394
[6]   Diagnosis of Non-small Cell Lung Cancer for Early Stage Asymptomatic Patients [J].
Goebel, Cherylle ;
Louden, Christopher L. ;
Mckenna, Robert, Jr. ;
Onugha, Osita ;
Wachtel, Andrew ;
Long, Thomas .
CANCER GENOMICS & PROTEOMICS, 2019, 16 (04) :229-244
[7]   Circulating tumor cells at each follow-up time point during therapy of metastatic breast cancer patients predict progression-free and overall survival [J].
Hayes, Daniel F. ;
Cristofanilli, Massimo ;
Budd, G. Thomas ;
Ellis, Matthew J. ;
Stopeck, Alison ;
Miller, M. Craig ;
Matera, Jeri ;
Allard, W. Jeffrey ;
Doyle, Gerald V. ;
Terstappen, Leon W. W. M. .
CLINICAL CANCER RESEARCH, 2006, 12 (14) :4218-4224
[8]   Identification of circulating tumor cells using 4-color fluorescence in situ hybridization: Validation of a noninvasive aid for ruling out lung cancer in patients with low-dose computed tomography-detected lung nodules [J].
Katz, Ruth L. ;
Zaidi, Tanweer M. ;
Pujara, Deep ;
Shanbhag, Namita D. ;
Truong, Duy ;
Patil, Shekhar ;
Mehran, Reza J. ;
El-Zein, Randa A. ;
Shete, Sanjay S. ;
Kuban, Joshua D. .
CANCER CYTOPATHOLOGY, 2020, 128 (08) :553-562
[9]   Genetically Abnormal Circulating Cells in Lung Cancer Patients: An Antigen-Independent Fluorescence In situ Hybridization-Based Case-Control Study [J].
Katz, Ruth L. ;
He, Weigong ;
Khanna, Abha ;
Fernandez, Ricardo L. ;
Zaidi, Tanweer M. ;
Krebs, Matthew ;
Caraway, Nancy P. ;
Zhang, Hua-Zhong ;
Jiang, Feng ;
Spitz, Margaret R. ;
Blowers, David P. ;
Jimenez, Carlos A. ;
Mehran, Reza J. ;
Swisher, Stephen G. ;
Roth, Jack A. ;
Morris, Jeffrey S. ;
Etzel, Carol J. ;
El-Zein, Randa .
CLINICAL CANCER RESEARCH, 2010, 16 (15) :3976-3987
[10]   Detection of mutations in EGFR in circulating lung-cancer cells [J].
Maheswaran, Shyamala ;
Sequist, Lecia V. ;
Nagrath, Sunitha ;
Ulkus, Lindsey ;
Brannigan, Brian ;
Collura, Chey V. ;
Inserra, Elizabeth ;
Diederichs, Sven ;
Iafrate, A. John ;
Bell, Daphne W. ;
Digumarthy, Subba ;
Muzikansky, Alona ;
Irimia, Daniel ;
Settleman, Jeffrey ;
Tompkins, Ronald G. ;
Lynch, Thomas J. ;
Toner, Mehmet ;
Haber, Daniel A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (04) :366-377