C-Net: A reliable convolutional neural network for biomedical image classification

被引:33
作者
Barzekar, Hosein [1 ]
Yu, Zeyun [1 ,2 ]
机构
[1] Univ Wisconsin, Dept Comp Sci, Big Data Analyt & Visualizat Lab, Milwaukee, WI 53211 USA
[2] Univ Wisconsin, Dept Biomed Engn, Milwaukee, WI 53211 USA
关键词
Biomedical image classification; Deep learning; Convolutional neural network; Histopathology; Computer-aided diagnosis; CANCER; LEVEL;
D O I
10.1016/j.eswa.2021.116003
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Cancers are the leading cause of death in many countries. Early diagnosis plays a crucial role in having proper treatment for this debilitating disease. The automated classification of the type of cancer is a challenging task since pathologists must examine a huge number of histopathological images to detect infinitesimal abnormalities. In this study, we propose a novel convolutional neural network (CNN) architecture composed of a Concatenation of multiple Networks, called C-Net, to classify biomedical images. The model incorporates multiple CNNs including Outer, Middle, and Inner. The first two parts of the architecture contain six networks that serve as feature extractors to feed into the Inner network to classify the images in terms of malignancy and benignancy. The C-Net is applied for histopathological image classification on two public datasets, including BreakHis and Osteosarcoma. To evaluate the performance, the model is tested using several evaluation metrics for its reliability. The C-Net model outperforms all other models on the individual metrics for both datasets and achieves zero misclassification. This approach has the potential to be extended to additional classification tasks, as experimental results demonstrate utilizing extensive evaluation metrics.
引用
收藏
页数:9
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