An oral, chemotherapy-free regimen (dasatinib plus prednisone) as induction and consolidation for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia

被引：3

作者：

Li, Xue-Ying ^{[1
,2
,3
]}

Qian, Jie-Jing ^{[1
,2
,3
]}

Yang, Min ^{[1
,2
,3
]}

Zhang, Yi ^{[1
,2
,3
]}

Wang, Sha-Sha ^{[1
,2
,3
]}

Meng, Hai-Tao ^{[1
,2
,3
]}

Yu, Wen-Juan ^{[1
,2
,3
]}

Tong, Hong-Yan ^{[1
,2
,3
]}

Ye, Xiu-Jin ^{[1
,2
,3
]}

Jin, Jie ^{[1
,2
,3
]}

Zhu, Hong-Hu ^{[1
,2
,3
]}

机构：

[1] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Dept Hematol, Hangzhou, Zhejiang, Peoples R China

[2] Zhejiang Univ, Zhejiang Prov Key Lab Hematol Oncol Diag & Treatm, Hangzhou, Zhejiang, Peoples R China

[3] Zhejiang Univ, Inst Hematol, Hangzhou, Zhejiang, Peoples R China

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2020年 / 189卷 / 06期

基金：

中国国家自然科学基金;

关键词：

IMATINIB; PHASE-2;

D O I：

10.1111/bjh.16661

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E231 / E234

页数：4

共 11 条

[1] Treatment of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia [J].

Abou Dalle, Iman ;

Jabbour, Elias ;

Short, Nicholas J. ;

Ravandi, Farhad .

CURRENT TREATMENT OPTIONS IN ONCOLOGY, 2019, 20 (01)

[2] A Phase 2 Trial of Ponatinib in Philadelphia Chromosome-Positive Leukemias [J].

Cortes, J. E. ;

Kim, D. -W. ;

Pinilla-Ibarz, J. ;

le Coutre, P. ;

Paquette, R. ;

Chuah, C. ;

Nicolini, F. E. ;

Apperley, J. F. ;

Khoury, H. J. ;

Talpaz, M. ;

DiPersio, J. ;

DeAngelo, D. J. ;

Abruzzese, E. ;

Rea, D. ;

Baccarani, M. ;

Mueller, M. C. ;

Gambacorti-Passerini, C. ;

Wong, S. ;

Lustgarten, S. ;

Rivera, V. M. ;

Clackson, T. ;

Turner, C. D. ;

Haluska, F. G. ;

Guilhot, F. ;

Deininger, M. W. ;

Hochhaus, A. ;

Hughes, T. ;

Goldman, J. M. ;

Shah, N. P. ;

Kantarjian, H. .

NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (19) :1783-1796

[3] Final report of a phase II study of imatinib mesylate with hyper-CVAD for the front-line treatment of adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia [J].

Daver, Naval ;

Thomas, Deborah ;

Ravandi, Farhad ;

Cortes, Jorge ;

Garris, Rebecca ;

Jabbour, Elias ;

Garcia-Manero, Guillermo ;

Borthakur, Gautam ;

Kadia, Tapan ;

Rytting, Michael ;

Konopleva, Marina ;

Kantarjian, Hagop ;

O'Brien, Susan .

HAEMATOLOGICA, 2015, 100 (05) :653-661

[4] UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia [J].

Fielding, Adele K. ;

Rowe, Jacob M. ;

Buck, Georgina ;

Foroni, Letizia ;

Gerrard, Gareth ;

Litzow, Mark R. ;

Lazarus, Hillard ;

Luger, Selina M. ;

Marks, David I. ;

McMillan, Andrew K. ;

Moorman, Anthony V. ;

Patel, Bella ;

Paietta, Elisabeth ;

Tallman, Martin S. ;

Goldstone, Anthony H. .

BLOOD, 2014, 123 (06) :843-850

[5] Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia [J].

Foa, Robin ;

Vitale, Antonella ;

Vignetti, Marco ;

Meloni, Giovanna ;

Guarini, Anna ;

De Propris, Maria Stefania ;

Elia, Loredana ;

Paoloni, Francesca ;

Fazi, Paola ;

Cimino, Giuseppe ;

Nobile, Francesco ;

Ferrara, Felicetto ;

Castagnola, Carlo ;

Sica, Simona ;

Leoni, Pietro ;

Zuffa, Eliana ;

Fozza, Claudio ;

Luppi, Mario ;

Candoni, Anna ;

Iacobucci, Ilaria ;

Soverini, Simona ;

Mandelli, Franco ;

Martinelli, Giovanni ;

Baccarani, Michele .

BLOOD, 2011, 118 (25) :6521-6528

[6]

Martinelli G, BLOOD S1, V130, P99

[7] US intergroup study of chemotherapy plus dasatinib and allogeneic stem cell transplant in Philadelphia chromosome positive ALL [J].

Ravandi, Farhad ;

Othus, Megan ;

O'Brien, Susan M. ;

Forman, Stephen J. ;

Ha, Chul S. ;

Wong, Jeffrey Y. C. ;

Tallman, Martin S. ;

Paietta, Elisabeth ;

Racevskis, Janis ;

Uy, Geoffrey L. ;

Horowitz, Mary ;

Takebe, Naoko ;

Little, Richard ;

Borate, Uma ;

Kebriaei, Partow ;

Kingsbury, Laura ;

Kantarjian, Hagop M. ;

Radich, Jerald P. ;

Erba, Harry P. ;

Appelbaum, Frederick R. .

BLOOD ADVANCES, 2016, 1 (03) :250-259

[8] Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia [J].

Ravandi, Farhad ;

O'Brien, Susan M. ;

Cortes, Jorge E. ;

Thomas, Deborah M. ;

Garris, Rebecca ;

Faderl, Stefan ;

Burger, Jan A. ;

Rytting, Michael E. ;

Ferrajoli, Alessandra ;

Wierda, William G. ;

Verstovsek, Srdan ;

Champlin, Richard ;

Kebriaei, Partow ;

McCue, Deborah A. ;

Huang, Xuelin ;

Jabbour, Elias ;

Garcia-Manero, Guillermo ;

Estrov, Zeev ;

Kantarjian, Hagop M. .

CANCER, 2015, 121 (23) :4158-4164

[9]

Short NJ, 2017, J CLIN ONCOL, V15, P7013

[10] Drug Resistance and BCR-ABL Kinase Domain Mutations in Philadelphia Chromosome- Positive Acute Lymphoblastic Leukemia From the Imatinib to the Second- Generation Tyrosine Kinase Inhibitor Era [J].

Soverini, Simona ;

De Benedittis, Caterina ;

Papayannidis, Cristina ;

Paolini, Stefania ;

Venturi, Claudia ;

Iacobucci, Ilaria ;

Luppi, Mario ;

Bresciani, Paola ;

Salvucci, Marzia ;

Russo, Domenico ;

Sica, Simona ;

Orlandi, Ester ;

Intermesoli, Tamara ;

Gozzini, Antonella ;

Bonifacio, Massimiliano ;

Rigolin, Gian Matteo ;

Pane, Fabrizio ;

Baccarani, Michele ;

Cavo, Michele ;

Martinelli, Giovanni .

CANCER, 2014, 120 (07) :1002-1009

← 1 2 →