Factor Analysis of the Clinical Characteristics of Primary Sjogren Syndrome

被引：10
|
作者：
Caffery, Barbara [1 ]
Simpson, Trefford [1 ]
Wang, Sunny [2 ]
Bailey, Denis [3 ]
McComb, John [4 ]
Rutka, John [5 ]
Slomovic, Allan [6 ]
Bookman, Arthur [7 ]
机构：
[1] Univ Waterloo, Sch Optometry, Waterloo, ON N2L 3G1, Canada
[2] Univ Toronto, Dept Stat & Actuarial Sci, Toronto, ON, Canada
[3] Univ Toronto, Div Pathol, Toronto, ON, Canada
[4] Univ Toronto, Div Dent, Toronto, ON, Canada
[5] Univ Toronto, Div Otolaryngol, Toronto, ON, Canada
[6] Univ Toronto, Div Ophthalmol, Toronto, ON, Canada
[7] Univ Toronto, Div Rheumatol, Univ Hlth Network, Toronto, ON, Canada
来源：
OPTOMETRY AND VISION SCIENCE | 2010年 / 87卷 / 10期
关键词：
Sjogren syndrome; dry eye; rose bengal staining; KERATOCONJUNCTIVITIS SICCA; DRY EYE; MANIFESTATIONS; MUCIN; CONJUNCTIVA; EXPRESSION; DIAGNOSIS; CRITERIA; TESTS; MUC16;
D O I：
10.1097/OPX.0b013e3181f32196
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose. The purpose of this study was to use factor analysis to analyze 90 clinical characteristics of a cohort of 231 patients with primary Sjogren syndrome (pSS). Methods. The records of all patients seen at the University Health Network Sjogren Syndrome Clinic from October 1992 to July 2006 were reviewed and documented. Those diagnosed as pSS by the American European Consensus Criteria of 2002 were included. The 90 clinical variables, including health history, blood analysis, symptoms of dry eye and dry mouth, salivary flow and biopsy, tear flow and staining, were analyzed by factor analysis. Results. Two hundred thirty-one patients with pSS charts were reviewed, and 90 variables were recorded. Factor analysis resulted in three factors: factor 1: ocular surface staining, factor 2: antimicrosomal antibodies and antithyroid antibodies, and factor 3: serum anti-Ro and anti-La. Conclusions. Ocular surface staining accounted for the greatest variance in this population of patients with pSS. (Optom Vis Sci 2010;87:742-750)
引用
收藏
页码：742 / 750
页数：9
相关论文
共 50 条
  • [21] IgA rheumatoid factor in primary Sjogren's syndrome
    Peen, E.
    Mellbye, O. J.
    Haga, H-J.
    SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 2009, 38 (01) : 46 - 49
  • [22] Clinical Analysis: Aqueous-Deficient and Meibomian Gland Dysfunction in Patients With Primary Sjogren's Syndrome
    Wang, Yi
    Qin, Qiyu
    Liu, Bo
    Fu, Yana
    Lin, Lin
    Huang, Xiaodan
    Jin, Xiuming
    FRONTIERS IN MEDICINE, 2019, 6
  • [23] Sjogren's syndrome
    Balint, Geza
    Buchanan, W. Watson
    Kean, Colin A.
    Kean, Walter
    Rainsford, K. D.
    INFLAMMOPHARMACOLOGY, 2024, 32 (01) : 37 - 43
  • [24] EXAMINING CLINICAL HETEROGENEITY IN PRIMARY SJOGREN'S SYNDROME: PROTEOMIC AND NETWORK ANALYSIS
    Berry, J.
    Casement, J.
    Traianos, E.
    Tarn, J.
    Ng, W. F.
    ANNALS OF THE RHEUMATIC DISEASES, 2023, 82 : 139 - 140
  • [25] Outcome of Pregnancy in Italian Patients with Primary Sjogren Syndrome
    Priori, Roberta
    Gattamelata, Angelica
    Modesti, Mariagrazia
    Colafrancesco, Serena
    Frisenda, Silvia
    Minniti, Antonina
    Framarino-dei-Malatesta, Marialuisa
    Maset, Marta
    Quartuccio, Luca
    De Vita, Salvatore
    Bartoloni, Elena
    Alunno, Alessia
    Gerli, Roberto
    Strigini, Francesca
    Baldini, Chiara
    Tani, Chiara
    Mosca, Marta
    Bombardieri, Stefano
    Valesini, Guido
    JOURNAL OF RHEUMATOLOGY, 2013, 40 (07) : 1143 - 1147
  • [26] Primary Sjogren's Syndrome as a Systemic Disease: A Study of Participants Enrolled in an International Sjogren's Syndrome Registry
    Malladi, Arundathi S.
    Sack, Kenneth E.
    Shiboski, Stephen C.
    Shiboski, Caroline H.
    Baer, Alan N.
    Banushree, Ratukondla
    Dong, Yi
    Helin, Pekka
    Kirkham, Bruce W.
    Li, Mengtao
    Sugai, Susumu
    Umehara, Hisanori
    Vivino, Frederick B.
    Vollenweider, Cristina F.
    Zhang, Wen
    Zhao, Yan
    Greenspan, John S.
    Daniels, Troy E.
    Criswell, Lindsey A.
    ARTHRITIS CARE & RESEARCH, 2012, 64 (06) : 911 - 918
  • [27] Clinical efficacy of the smartplug™ in the treatment of primary Sjogren’s syndrome with keratoconjunctivitis SICCA: one-year follow-up study
    Sait Egrilmez
    Fatih Aslan
    Gonca Karabulut
    Yasemin Kabasakal
    Ayse Yagci
    Rheumatology International, 2011, 31 : 1567 - 1570
  • [28] Clinical efficacy of the smartplug™ in the treatment of primary Sjogren's syndrome with keratoconjunctivitis SICCA: one-year follow-up study
    Egrilmez, Sait
    Aslan, Fatih
    Karabulut, Gonca
    Kabasakal, Yasemin
    Yagci, Ayse
    RHEUMATOLOGY INTERNATIONAL, 2011, 31 (12) : 1567 - 1570
  • [29] Associations between ocular and extra-ocular assessment in primary Sjogren's syndrome
    Da Cunha, Elodie
    Mariette, Xavier
    Desmoulins, Frederic
    Berge, Elisabeth
    Nocturne, Gaetane
    Benmalek, Anouar
    Haigh, Oscar
    Seror, Raphaele
    Labetoulle, Marc
    Rousseau, Antoine
    JOINT BONE SPINE, 2022, 89 (05)
  • [30] A Pilot Study of a Panel of Ocular Inflammation Biomarkers in Patients with Primary Sjogren's Syndrome
    Boto de los Bueis, Ana
    de la Fuente, Miguel
    Montejano-Milner, Rafael
    del Hierro Zarzuelo, Almudena
    Vecino, Elena
    Acera, Arantxa
    CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023, 45 (04) : 2881 - 2894
12345