Recent advances in pharmacological research on Ecklonia species: a review

被引:31
作者
Koirala, Prashamsa [1 ]
Jung, Hyun Ah [2 ]
Choi, Jae Sue [1 ]
机构
[1] Pukyong Natl Univ, Dept Food & Life Sci, Busan 48513, South Korea
[2] Chonbuk Natl Univ, Dept Food Sci & Human Nutr, Jeonju 54896, South Korea
基金
新加坡国家研究基金会;
关键词
Brown seaweed; Ecklonia; Therapeutic potential; EDIBLE BROWN-ALGAE; INDUCED OXIDATIVE STRESS; NF-KAPPA-B; ALLEVIATES POSTPRANDIAL HYPERGLYCEMIA; IN-VITRO; MARINE-ALGAE; INHIBITS ADIPOGENESIS; SULFATED POLYSACCHARIDES; ANTIPLASMIN INHIBITOR; UNDARIA-PINNATIFIDA;
D O I
10.1007/s12272-017-0948-4
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The genus Ecklonia (Lessoniaceae, Phaeophyceae), commonly called kelp (brown algae), is abundant on the coasts of Japan and Korea. During the past few decades, Ecklonia species have received tremendous attention for their wide range of therapeutic properties and multiple health benefits, such as great nutritional value and being rich in vitamins, minerals, dietary fiber, proteins, and polysaccharides. Several novel functional ingredients with diversified biological activities have been isolated and possess antimicrobial, antiviral, hepatoprotective, cardioprotective, anti-inflammatory, neuroprotective, anticarcinogenic, immunomodulatory, hypolipidemic, anti-diabetic, and antioxidant therapeutic properties. The present review discusses the phytochemical, pharmacological, therapeutic, nutritional, and health benefits of different species of genus Ecklonia, as well as their use in the prevention of disease and maintenance of good health.
引用
收藏
页码:981 / 1005
页数:25
相关论文
共 166 条
[21]   Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABAA receptor [J].
Cho, Suengmok ;
Yoon, Minseok ;
Pae, Ae Nim ;
Jin, Young-Ho ;
Cho, Nam-Chul ;
Takata, Yohko ;
Urade, Yoshihiro ;
Kim, Sojin ;
Kim, Jin-Soo ;
Yang, Hyejin ;
Kim, Jiyoung ;
Kim, Jinkyoung ;
Han, Jin-Kyu ;
Shimizu, Makoto ;
Huang, Zhi-Li .
PSYCHOPHARMACOLOGY, 2014, 231 (14) :2825-2837
[22]   Multifunctional Activity of Polyphenolic Compounds Associated with a Potential for Alzheimer's Disease Therapy from Ecklonia cava [J].
Choi, Byoung Wook ;
Lee, Hye Sook ;
Shin, Hyeon-Cheol ;
Lee, Bong Ho .
PHYTOTHERAPY RESEARCH, 2015, 29 (04) :549-553
[23]   Suppression of NF-κB by Dieckol Extracted from Ecklonia cava Negatively Regulates LPS Induction of Inducible Nitric Oxide Synthase Gene [J].
Choi, Hye-Jin ;
Park, Jung-Hwan ;
Lee, Bong Ho ;
Chee, Hee Youn ;
Lee, Kyung Bok ;
Oh, Sang-Muk .
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2014, 173 (04) :957-967
[24]   Dieckol, a major phlorotannin in Ecklonia cava, suppresses lipid accumulation in the adipocytes of high-fat diet-fed zebrafish and mice: Inhibition of early adipogenesis via cell-cycle arrest and AMPK activation [J].
Choi, Hyeon-Son ;
Jeon, Hui-Jeon ;
Lee, Ok-Hwan ;
Lee, Boo-Yong .
MOLECULAR NUTRITION & FOOD RESEARCH, 2015, 59 (08) :1458-1471
[25]  
Choi JS, 2011, J ENVIRON BIOL, V32, P313
[27]  
Chowdhury MTH, 2014, J ENVIRON BIOL, V35, P713
[28]   Molecular origins of cancer: Oncogenes and cancer [J].
Croce, Carlo M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (05) :502-511
[29]   Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways [J].
Cui, Yanji ;
Park, Jee-Yun ;
Wu, Jinji ;
Lee, Ji Hyung ;
Yang, Yoon-Sil ;
Kang, Moon-Seok ;
Jung, Sung-Cherl ;
Park, Joo Min ;
Yoo, Eun-Sook ;
Kim, Seong-Ho ;
Jo, Sangmee Ahn ;
Suk, Kyoungho ;
Eun, Su-Yong .
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY, 2015, 19 (03) :219-228
[30]   Matrix Metalloproteinase Inhibitors A Critical Appraisal of Design Principles and Proposed Therapeutic Utility [J].
Dorman, Gyoergy ;
Cseh, Sandor ;
Hajdu, Istvan ;
Barna, Laszlo ;
Konya, Denes ;
Kupai, Krisztina ;
Kovacs, Laszlo ;
Ferdinandy, Peter .
DRUGS, 2010, 70 (08) :949-964