Recent advances in pharmacological research on Ecklonia species: a review

被引：31
作者：
Koirala, Prashamsa [1 ]
Jung, Hyun Ah [2 ]
Choi, Jae Sue [1 ]
机构：
[1] Pukyong Natl Univ, Dept Food & Life Sci, Busan 48513, South Korea
[2] Chonbuk Natl Univ, Dept Food Sci & Human Nutr, Jeonju 54896, South Korea
来源：
ARCHIVES OF PHARMACAL RESEARCH | 2017年 / 40卷 / 09期
基金：
新加坡国家研究基金会;
关键词：
Brown seaweed; Ecklonia; Therapeutic potential; EDIBLE BROWN-ALGAE; INDUCED OXIDATIVE STRESS; NF-KAPPA-B; ALLEVIATES POSTPRANDIAL HYPERGLYCEMIA; IN-VITRO; MARINE-ALGAE; INHIBITS ADIPOGENESIS; SULFATED POLYSACCHARIDES; ANTIPLASMIN INHIBITOR; UNDARIA-PINNATIFIDA;
D O I：
10.1007/s12272-017-0948-4
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The genus Ecklonia (Lessoniaceae, Phaeophyceae), commonly called kelp (brown algae), is abundant on the coasts of Japan and Korea. During the past few decades, Ecklonia species have received tremendous attention for their wide range of therapeutic properties and multiple health benefits, such as great nutritional value and being rich in vitamins, minerals, dietary fiber, proteins, and polysaccharides. Several novel functional ingredients with diversified biological activities have been isolated and possess antimicrobial, antiviral, hepatoprotective, cardioprotective, anti-inflammatory, neuroprotective, anticarcinogenic, immunomodulatory, hypolipidemic, anti-diabetic, and antioxidant therapeutic properties. The present review discusses the phytochemical, pharmacological, therapeutic, nutritional, and health benefits of different species of genus Ecklonia, as well as their use in the prevention of disease and maintenance of good health.
引用
收藏
页码：981 / 1005
页数：25
相关论文
共 166 条
[1]   Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimer's Disease [J].
Agostinho, Paula ;
Cunha, Rodrigo A. ;
Oliveira, Catarina .
CURRENT PHARMACEUTICAL DESIGN, 2010, 16 (25) :2766-2778
[2]  
Agrawal R., 2013, Int. J. Sci. Eng. Res, V10, P1093
[3]   Dioxinodehydroeckol Enhances the Differentiation of Osteoblasts by Regulating the Expression of Phospho-Smad1/5/8 [J].
Ahn, Byul-Nim ;
Karadeniz, Fatih ;
Kong, Chang-Suk ;
Nam, Ki-Ho ;
Jang, Mi-Soon ;
Seo, Youngwan ;
Kim, Han Seong .
MARINE DRUGS, 2016, 14 (09)
[4]   Dieckol, a phlorotannin of Ecklonia cava, suppresses IgE-mediated mast cell activation and passive cutaneous anaphylactic reaction [J].
Ahn, Ginnae ;
Amagai, Yosuke ;
Matsuda, Akira ;
Kang, Sung-Myung ;
Lee, WonWoo ;
Jung, Kyungsook ;
Oida, Kumiko ;
Jang, Hyosun ;
Ishizaka, Saori ;
Matsuda, Kenshiro ;
Jeon, You-Jin ;
Jee, Youngheun ;
Matsuda, Hiroshi ;
Tanaka, Akane .
EXPERIMENTAL DERMATOLOGY, 2015, 24 (12) :968-970
[5]  
Ahn G, 2015, EXCLI J, V14, P294, DOI 10.17179/excli2014-676
[6]   The JNK/NFκB pathway is required to activate murine lymphocytes induced by a sulfated polysaccharide from Ecklonia cava [J].
Ahn, Ginnae ;
Bing, So Jin ;
Kang, Sung-Myung ;
Lee, Won-Woo ;
Lee, Seung-Hong ;
Matsuda, Hiroshi ;
Tanaka, Akane ;
Cho, Ik-Hyun ;
Jeon, You-Jin ;
Jee, Youngheun .
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 1830 (03) :2820-2829
[7]   Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth [J].
Ahn, Ji-Hye ;
Yang, Yeong-In ;
Lee, Kyung-Tae ;
Choi, Jung-Hye .
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2015, 141 (02) :255-268
[8]  
[Anonymous], 1828, Kgl Dan lid Selsk Naturvid Math Afd
[9]   Anti-HIV-1 activity of phloroglucinol derivative, 6,6′-bieckol, from Ecklonia cava [J].
Artan, Murat ;
Li, Yong ;
Karadeniz, Fatih ;
Lee, Sang-Hoon ;
Kim, Moon-Moo ;
Kim, Se-Kwon .
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (17) :7921-7926
[10]  
Bae Min Joo, 2015, Prev Nutr Food Sci, V20, P153, DOI 10.3746/pnf.2015.20.3.153
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