NOESY on neurotoxins: NMR and conformational assignments of picrotoxins

被引:0
|
作者
Perry, NB
Aiyaz, M
Kerr, DS
Lake, RJ
Leach, MT
机构
[1] Univ Otago, New Zealand Inst Crop & Food Res Ltd, Dept Chem, Dunedin, New Zealand
[2] Univ Otago, Sch Med, Dept Pharmacol, Dunedin, New Zealand
[3] Inst Environm Sci & Res Ltd, Christchurch, New Zealand
关键词
NMR; nuclear Overhauser effect; conformation; neurotoxin; picrotoxanes; Coriaria sarmentosa;
D O I
10.1002/1099-1565(200101/02)12:1<69::AID-PCA563>3.0.CO;2-M
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Nuclear Overhauser effect spectroscopy (NOESY) gave full assignments of the H-1-NMR spectra of the picrotoxane neurotoxins tutin, hyenanchin, picrotoxinin and picrotin, as well as the solution conformations of these compounds, consistent with molecular modelling. Fully assigned C-13-NMR data are reported. Copyright (C) 2001 John Wiley & Sons, Ltd.
引用
收藏
页码:69 / 72
页数:4
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