NOESY on neurotoxins: NMR and conformational assignments of picrotoxins

被引:0
|
作者
Perry, NB
Aiyaz, M
Kerr, DS
Lake, RJ
Leach, MT
机构
[1] Univ Otago, New Zealand Inst Crop & Food Res Ltd, Dept Chem, Dunedin, New Zealand
[2] Univ Otago, Sch Med, Dept Pharmacol, Dunedin, New Zealand
[3] Inst Environm Sci & Res Ltd, Christchurch, New Zealand
关键词
NMR; nuclear Overhauser effect; conformation; neurotoxin; picrotoxanes; Coriaria sarmentosa;
D O I
10.1002/1099-1565(200101/02)12:1<69::AID-PCA563>3.0.CO;2-M
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Nuclear Overhauser effect spectroscopy (NOESY) gave full assignments of the H-1-NMR spectra of the picrotoxane neurotoxins tutin, hyenanchin, picrotoxinin and picrotin, as well as the solution conformations of these compounds, consistent with molecular modelling. Fully assigned C-13-NMR data are reported. Copyright (C) 2001 John Wiley & Sons, Ltd.
引用
收藏
页码:69 / 72
页数:4
相关论文
共 50 条
  • [1] NMR ASSIGNMENTS AND CONFORMATIONAL-ANALYSIS OF YUANHUACIN
    ZHOU, BN
    XUE, L
    LIN, LZ
    LIN, LJ
    JOHNSON, ME
    CORDELL, GA
    MAGNETIC RESONANCE IN CHEMISTRY, 1993, 31 (02) : 194 - 199
  • [2] NMR H-1 RELAXATION AND NOESY STUDIES OF SPIPERONE CONFORMATIONAL FEATURES IN SOLUTION
    KELLER, CE
    CARPER, WR
    MAGNETIC RESONANCE IN CHEMISTRY, 1993, 31 (06) : 566 - 572
  • [3] Conformational Assignments of Thujopsene and Related Compounds
    Yaoita, Yasunori
    Machida, Koichi
    NATURAL PRODUCT COMMUNICATIONS, 2019, 14 (09)
  • [4] Conformational evaluation and detailed 1H and 13C NMR assignments of eremophilanolides
    Burgueño-Tapia, E
    Hernández, LR
    Reséndiz-Villalobos, AY
    Joseph-Nathan, P
    MAGNETIC RESONANCE IN CHEMISTRY, 2004, 42 (10) : 887 - 892
  • [5] NMR assignments and conformational studies of new C-3-cyclotriveratrylenes with pendant thiol substituents
    Bougault, C
    Jordanov, J
    Bardet, M
    MAGNETIC RESONANCE IN CHEMISTRY, 1996, 34 (01) : 24 - 32
  • [6] Conformational State of Fenamates at the Membrane Interface: A MAS NOESY Study
    Khodov, Ilya A.
    Belov, Konstantin V.
    Huster, Daniel
    Scheidt, Holger A.
    MEMBRANES, 2023, 13 (06)
  • [7] IDENTIFICATION OF MODIFIED NATURAL PORPHYRIN ISOMERS - H-1 AND C-13 NMR ASSIGNMENTS BY NOESY AND REVERSE HETERONUCLEAR SHIFT CORRELATION
    BONDON, A
    AUTRET, M
    SIMONNEAUX, G
    MAGNETIC RESONANCE IN CHEMISTRY, 1994, 32 (02) : 78 - 82
  • [8] 1H and 13C NMR assignments and conformational analysis of some podocarpene derivatives
    Arnó, M
    González, MA
    Marín, ML
    Zaragozá, RJ
    MAGNETIC RESONANCE IN CHEMISTRY, 2000, 38 (12) : 1019 - 1022
  • [9] 13C NMR assignments and conformational evaluation of diterpenes from Croton sarcopetalus Muell.
    de Heluani, CS
    Catalán, CAN
    Hernández, LR
    Burgueño-Tapia, E
    Joseph-Nathan, P
    MAGNETIC RESONANCE IN CHEMISTRY, 1998, 36 (12) : 947 - 950
  • [10] NMR assignments and conformation of taraxerenes
    Bates, RB
    Jacobsen, NE
    Setzer, WN
    Stessman, CC
    MAGNETIC RESONANCE IN CHEMISTRY, 1998, 36 (07) : 539 - 541