Mimicking Membrane-Related Biological Events by DNA Origami Nanotechnology

被引：31
|
作者：
Suzuki, Yuki [1 ,3 ]
Endo, Masayuki [2 ,3 ]
Sugiyama, Hiroshi [1 ,2 ,3 ]
机构：
[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan
[2] Kyoto Univ, Inst Integrated Cell Mat Sci WPI iCeMS, Sakyo Ku, Kyoto 6068501, Japan
[3] Japan Sci & Technol Agcy JST, CREST, Chiyoda Ku, Tokyo 1020075, Japan
来源：
ACS NANO | 2015年 / 9卷 / 04期
关键词：
NANOSTRUCTURES; NANOPORES; CLATHRIN;
D O I：
10.1021/acsnano.5b01723
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
One of the potential applications of DNA nanotechnology is the construction of two- or three-dimensional nanostructures that mimic the function of existing biological molecules. In this issue of ACS Nano, Kocabey et aL demonstrate that lipid-bilayer-anchored DNA origami structures can be assembled into prescribed superstructures in a programmed manner. The reported DNA-based artificial system can mimic the dynamic assembly of membrane-associated protein clusters that play an essential role in deformation of cellular membranes.
引用
收藏
页码：3418 / 3420
页数：3
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