Enhancement of the efficiency of magnetic targeting for drug delivery: Development and evaluation of magnet system

被引：55

作者：

Cao, Quanliang ^{[1
]}

Han, Xiaotao ^{[1
]}

Li, Liang ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Wuhan Natl High Magnet Field Ctr, Wuhan 430074, Peoples R China

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2011年 / 323卷 / 15期

关键词：

Magnetic targeted drug delivery system; Magnetic nanoparticle; Magnetic force; Magnet system design; IN-VITRO; NANOPARTICLES; FIELD; PARTICLE; DEEP; GENE; PRINCIPLES; CAPTURE; SIZE;

D O I：

10.1016/j.jmmm.2010.11.058

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Deep magnetic capture and clinical application are the current trends for magnetic targeted drug delivery system. More promising and possible strategies are needed to overcome the current limitations and further improve the magnetic targeting technique. Recent advances in the development of targeting magnet system show promise in progressing this technology from the laboratory to the clinic. Starting from well-known basic concepts, current limitations of magnetic targeted drug delivery system are analyzed. Meanwhile, the design concepts and evaluations of some effective improvements in magnet system are discussed and reviewed with reference to (i) reasonable design of magnet system; (ii) control modes of magnet system used to generate dynamical magnetic fields; and (iii) magnetic field driving types. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：1919 / 1924

页数：6

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