Association between wrist ratio and carpal tunnel syndrome: Effect modification by body mass index

被引:12
作者
Thiese, Matthew S. [1 ]
Merryweather, Andrew [2 ]
Koric, Alzina [1 ]
Ott, Ulrike [1 ]
Wood, Eric M. [1 ]
Kapellusch, Jay [3 ]
Foster, James [3 ]
Garg, Arun [3 ]
Deckow-Schaefer, Gwen [4 ]
Tomich, Suzanna [5 ]
Kendall, Richard [6 ]
Drury, David L. [7 ]
Wertsch, Jacqueline [8 ]
Hegmann, Kurt T. [1 ]
机构
[1] Univ Utah, Rocky Mt Ctr Occupat & Environm Hlth, 391 Chipeta Way,Suite C, Salt Lake City, UT 84108 USA
[2] Univ Utah, Dept Mech Engn, Salt Lake City, UT 84112 USA
[3] Univ Wisconsin, Ctr Ergon, Milwaukee, WI 53201 USA
[4] Encore Unlimited LLC, Stevens Point, WI USA
[5] Argent, Waukesha, WI USA
[6] Univ Utah, Dept Phys Med & Rehabil, Salt Lake City, UT USA
[7] Allina Hlth Clin, Minneapolis, MN USA
[8] Med Coll Wisconsin, Dept Phys Med & Rehabil, Milwaukee, WI 53226 USA
关键词
carpal tunnel syndrome; effect modification; nerve conduction study; obesity; wrist; EXTREMITY MUSCULOSKELETAL DISORDERS; RISK-FACTORS; MEDIAN NERVE; WORKING POPULATION; GENERAL-POPULATION; CANAL PRESSURES; HAND; PREVALENCE; DIAGNOSIS; GENDER;
D O I
10.1002/mus.25692
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
IntroductionPrevious studies have reported higher wrist ratios (WR) related to carpal tunnel syndrome (CTS) but have not assessed effect modification by obesity and may have inadequately controlled for confounders. MethodsBaseline data of a multicenter prospective cohort study were analyzed. CTS was defined by nerve conduction study (NCS) criteria and symptoms. ResultsAmong the 1,206 participants, a square-shaped wrist was associated with CTS after controlling for confounders (prevalence ratio=2.27; 95% confidence interval [95% CI], 1.33-3.86). Body mass index (BMI) was a strong effect modifier on the relationship between WR and both CTS and abnormal NCS results, with normal weight strata of rectangular versus square wrists=8.18 (95% CI, 1.63-49.96) and 7.12 (95% CI, 2.19-23.16), respectively. DiscussionA square wrist is significantly associated with CTS after controlling for confounders. Effect modification by high BMI masked the eightfold magnitude adjusted relationship seen between WR and CTS among normal weight participants. Muscle Nerve56: 1047-1053, 2017
引用
收藏
页码:1047 / 1053
页数:7
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