Helicobacter pylori and its association with autoimmune diseases: systemic lupus erythematosus, rheumatoid arthritis and Sjogren syndrome

被引:10
作者
Etchegaray-Morales, Ivet [1 ]
Alejandro Jimenez-Herrera, Erick [2 ]
Mendoza-Pinto, Claudia [1 ,3 ]
Rojas-Villarraga, Adriana [4 ]
Macias-Diaz, Salvador [5 ,6 ]
David Osorio-Pena, Angel [1 ]
Munguia-Realpozo, Pamela [1 ]
Garcia-Carrasco, Mario [1 ]
机构
[1] Meritorious Autonomous Univ Puebla, Med Sch, Dept Rheurnatol, 13 Sur 2702, Puebla 72420, Mexico
[2] Dermatol Ctr Dr Ladislao de la Pascua, Dr Jose Maria Vertiz 464, Mexico City 06780, DF, Mexico
[3] Mexican Social Secur Inst, Hosp UMAE, Unit Specialties, Syst Autoimmune Dis Res, 2 Norte 2004, Puebla 72000, Mexico
[4] Univ Hlth Sci, Fdn Univ Ciencias Salud, Res Inst, Cra 19 N 8a-32, Bogota, Colombia
[5] Inst Mexican Seguro Social, Hosp Gen Zona 1, Internal Med Serv, Ave Francisco I Madero 407, Pachuca 42070, Hidalgo, Mexico
[6] Meritorious Autonomous Univ, Dept Med Oncol, Med Sch, 13 Sur 2702, Puebla 72420, Mexico
关键词
Helicobacter pylori; Systemic lupus erythematosus; Rheumatoid arthritis; Sjogren; Syndrome; Infection; INTRAMUSCULAR GOLD THERAPY; LYMPHOID-TISSUE; INFECTION; ERADICATION; SEROPREVALENCE; PATHOGENESIS; INFLAMMATION; ANTIBODIES; MICROBIOTA; DISORDERS;
D O I
10.1016/j.jtauto.2021.100135
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Helicobacter pylori (H. pylori) is a gram-negative bacterium that adapts to the gastric mucosa and provokes symptoms associated with gastritis. Chronic H. pylori infection in patients with a genetic predisposition can trigger autoimmune diseases due to the immune interaction of cellular and humoral responses. Infections are a triggering factor for systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and Sjogren syndrome (SS), although the association between H. pylori and these diseases is unclear. Therefore, we reviewed this interaction and its clinical importance.
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页数:7
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