Transport of fragmented DNA in apical dendrites of gerbil CA1 pyramidal neurons following transient forebrain ischemia

被引：15
作者：
Hara, A
Niwa, M
Iwai, T
Nakashima, M
Yano, H
Uematsu, T
Yoshimi, N
Mori, H
机构：
[1] Gifu Univ, Sch Med, Dept Pathol, Gifu 5008705, Japan
[2] Gifu Univ, Sch Med, Dept Pharmacol, Gifu 5008705, Japan
[3] Gifu Univ, Sch Med, Dept Neurosurg, Gifu 5008705, Japan
来源：
BRAIN RESEARCH | 1998年 / 806卷 / 02期
关键词：
delayed neuronal death; gerbil; DNA fragmentation; forebrain ischemia; apical dendrite;
D O I：
10.1016/S0006-8993(98)00753-7
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Transport of fragmented DNA in apical dendrites of the CAI pyramidal neurons of gerbil hippocampus is observed in the apoptotic process following transient forebrain ischemia. The time-course of specific DNA fragmentation was examined after the ischemic insult by in situ nick-end-labeling method and fluorescence detection technique by DAPI. Although the role of the fragmented DNA movement is unclear, the transport mechanism of fragmented DNA is still active in the late phase of apoptotic process. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：274 / 277
页数：4
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