Response, Survival, and Prognostic Factors After Hepatic Arterial Chemoembolization in Patients With Liver Metastases From Cutaneous Melanoma

被引：16
作者：
Ahrar, Judy
Gupta, Sanjay [1 ]
Ensor, Joe [2 ]
Ahrar, Kamran
Madoff, David C.
Wallace, Michael J.
Murthy, Ravi
Tam, Alda
Hwu, Patrick [3 ]
Bedikian, Agop Y. [3 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Diagnost Radiol, Unit 325, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Biostat, Houston, TX 77030 USA
[3] Univ Texas MD Anderson Canc Ctr, Dept Melanoma Med Oncol, Houston, TX 77030 USA
来源：
CANCER INVESTIGATION | 2011年 / 29卷 / 01期
关键词：
OCULAR MELANOMA; MALIGNANT-MELANOMA; UVEAL MELANOMA; DISTANT METASTASES; POLYVINYL SPONGE; UNITED-STATES; CHEMOTHERAPY; EMBOLIZATION; CISPLATIN; FOTEMUSTINE;
D O I：
10.3109/07357907.2010.535052
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We reviewed the medical records of 42 patients with cutaneous melanoma metastatic to the liver who underwent hepatic artery chemoembolization (HACE) at our institution. HACE resulted in radiologic response (38.9%) or disease stabilization (47.2%) in most patients. The median overall survival (OS) and time to progression (TTP) of liver disease were 7.7 and 6 months, respectively. Patient's age, lactate dehydrogenase (LDH) levels, type of treatment, number of extrahepatic metastatic sites, and response to therapy were found to be significant predictors of OS after HACE. Prolonged survival was seen in patients who responded to HACE (p = .034).</.
引用
收藏
页码：49 / 55
页数：7
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